After securing their place in the next round of the cup, Arsenal immediately rested and regrouped.
Their first-team regulars were primed and ready for the crucial fifth match of the UEFA Champions League Group Stage.
This Champions League clash promised to be the decisive battle for top spot in the group.
Arsenal were back at Emirates Stadium, hosting Bundesliga heavyweights Dortmund once again.
In their first meeting, Arsenal had stormed Dortmund's intimidating home ground and crushed them by four goals.
That devastating defeat had become Dortmund's most searing humiliation of the season.
Ever since, Borussia Dortmund had swallowed their bitterness, trained relentlessly, and worked their way back into form.
Successive group-stage victories had kept them firmly in contention for qualification, with hope of closing the points gap still alive.
Now, traveling to London to challenge Arsenal, Dortmund were fired up and determined to exact revenge.
At their pre-match press conference, Borussia Dortmund boldly declared that they would not accept losing both encounters.
They would throw themselves into the fiercest challenges and launch relentless attacks to halt Arsenal's winning streak.
The German media fueled the anticipation, arguing that Borussia Dortmund had completed their recovery and now had what it took to avenge their defeat.
Victory here would allow Borussia Dortmund to narrow the points gap and keep the battle for first place alive.
For Arsenal, this match was equally significant. They could not afford a slip.
With four wins from four Champions League matches, they sat comfortably atop the group, their qualification prospects looking excellent.
A home victory over Dortmund would secure qualification as group winners with a match to spare.
Five wins from five would send them powering into the Champions League round of sixteen with a perfect record, creating another extraordinary milestone.
To secure victory in this crucial contest,