Tsunade

Biodata

Feature	Details
Name	Tsunade (纲手)
Alias(es)	Lady Tsunade; Fifth Hokage; one of the Legendary Sannin 85 143 144
Gender	Female
Clan / Bloodline	Senju clan; Senju Constitution 84 143
Affiliation	Konoha; later supports Konoha's merger into Hidden Mystic 144 313 322
Occupation / Role	Fifth Hokage; medical ninja; political leader 144 263
Status	Alive 365
First Appearance	Chapter 85

Power Progression

Stage / Realm / Level	Chapter	Notes
Kage-level — S-rank rating	84	The system identifies her as a Kage-level shinobi with an S-rank overall rating and the Senju Constitution.
Wood Release awakened	349	Xuandou uses a Wood Release Awakening Card on her, raising her strength another step.
Rebirth: Strength of a Hundred Technique	351	Activates the technique against Kashin Koji, manifesting black markings and greatly amplifying her close-range fighting power.

Background

Tsunade is the granddaughter of the First Hokage, Senju Hashirama, and a student of the Third Hokage, Hiruzen Sarutobi. Her lineage, strength, and reputation as one of the Legendary Sannin make her a widely respected figure in the shinobi world. 143

Before returning to Konoha, she traveled with her apprentice Shizune and accumulated gambling debts. During this period, she first encountered Uchiha Gento outside a casino. 85 144

Repeated wartime losses—including her parents, younger brother Nawaki, and lover Dan Katō—left Tsunade with hemophobia and a lasting aversion to war. Even after Hashirama's revival, her fear of losing loved ones persists, especially regarding her son Xi He. 312

Appearance

Tsunade is a blonde Senju woman with a diamond-shaped mark on her forehead, a mature bearing, and an assertive, heroic presence. She commonly wears a tea-colored robe beneath a green haori marked with the kanji for “Gambling,” along with wooden geta. 85

• Long blonde hair and a diamond-shaped forehead mark. 85
• Typically wears a green haori over a tea-colored outfit. 85 154
• Carries herself with visible confidence and unruliness. 85
• Wore a deep-purple two-piece swimsuit while visiting the Uchiha clan's Desire Hot Spring. 154

Personality

Tsunade is blunt, forceful, and unwilling to tolerate incompetence. Immediately after becoming Hokage, she confronts Konoha's political paralysis, demands that the major clans contribute to the village's defense, and dismisses Mitokado Homura and Utatane Koharu when they obstruct her plans. She reinforces the dismissal by smashing the meeting table with a single punch. 144

Despite her temper, she is a pragmatic leader focused on Konoha's survival. She pursues an alliance with Hidden Xuan Village when Konoha is under attack, later investigates entrenched corruption among the village elders, and redirects confiscated wealth toward pensions, war victims, and training new shinobi. 144 180 182

Her personal losses make her deeply wary of war and fiercely protective of Xi He. She initially questions Xuandou's methods of unification, but ultimately supports Konoha's cooperation with Hidden Mystic in the hope of ending the cycle of conflict. 215 312 313

Abilities & Skills

Medical Ninjutsu

Tsunade is described as the strongest medical ninja in the shinobi world. Her medical expertise also informs her political priorities, including the deployment and training of medical ninja personnel. 153 178 263

• Supports cooperation between Konoha and Hidden Xuan Village to train additional medical ninjas. 178 182
• Views medical research as a means to save lives, including the study of pathology with a deceased person's family's consent. 215
• Intends to develop the Rebirth: Strength of a Hundred Technique further after witnessing Hanyu's battle. 344

Chakra-Enhanced Strength

Tsunade channels immense force through her physical strikes.

• Shatters a long conference table with one punch while dismissing Konoha's two advisors. 144
• Uses her overwhelming strength to vent her anger on Xuandou after learning Xi He faced danger without her knowledge. 312
• Combines her strength-based fighting style with Wood Release and medical techniques in battle. 349 351

Wood Release

Xuandou awakens Tsunade's Wood Release using an Awakening Card, increasing her combat strength. 349

• Prepares to intervene with Wood Release after seeing a ninja who resembles Jiraiya under attack. 349
• Her Senju vitality and close-combat style are noted as especially suited to the endurance granted by Wood Release. 349

Rebirth: Strength of a Hundred Technique

Tsunade activates the Rebirth: Strength of a Hundred Technique during her battle with Kashin Koji. 351

• Produces black band-like markings across her body when activated. 351
• Enhances her power for sustained close-quarters combat. 351
• Is deployed alongside another S-rank medical ninjutsu against Kashin Koji. 351

Relationships

• Senju Hashirama — Her grandfather. She is emotionally overwhelmed by his resurrection, while Hashirama quickly embraces his role as Xi He's great-grandfather. 216
• Hiruzen Sarutobi — Her former teacher and predecessor as Hokage. Tsunade succeeds him after his death but condemns the political failures that occurred under his administration. 143 144
• Jiraiya — Fellow Sannin, childhood companion, and political supporter. He helps bring her back to Konoha and remains to assist her administration. 143 144
• Shizune Kato — Her apprentice and close attendant. Shizune accompanies Tsunade during her travels, assists with Hokage duties, and supports her as a mother. 85 190
• Uchiha Gento / Xuandou — Political ally and the father of her son, Xi He. Their relationship strengthens cooperation between Konoha and Hidden Mystic, though Tsunade repeatedly resists his manipulation and unilateral actions. 190 215 313 332
• Uchiha Xi He — Her son with Gento. Tsunade is fiercely protective of him and remains involved in his upbringing despite her Hokage duties. 190 216 312
• Mitokado Homura and Utatane Koharu — Former Konoha advisors whom Tsunade removes from office, investigates for corruption, and ultimately sees executed after their crimes are exposed. 144 180 182

Story Role / Major Arcs

Fifth Hokage and Konoha's Defense

After Hiruzen's death, Tsunade becomes the Fifth Hokage during a crisis in which Konoha faces invasions from three enemy villages. She calls the major clan heads together, seeks manpower for the front, and identifies an alliance with the Uchiha as necessary for survival. 144

She strips Homura and Koharu of their advisory positions after denouncing their failures, obstruction, and role in Konoha's decline. 144

Alliance with Hidden Xuan Village

Tsunade travels to Hidden Xuan Village to request Uchiha aid for Konoha. After the Uchiha defeat Kumogakure and deter further attacks from Sunagakure and Iwagakure, Konoha and the Uchiha establish a military alliance. 153 165

She later negotiates mission cooperation with Gento: Konoha supplies manpower while the Uchiha provide credibility, with profits divided in Konoha's favor. 167

Anti-Corruption Reforms

When Gento threatens Homura and Koharu, Tsunade prevents their immediate execution in order to preserve due process and Konoha's political stability. She instead orders an Anbu investigation into their families. 179 180

The investigation reveals massive unexplained assets and wider corruption. Following the advisors' execution, Tsunade allocates the recovered wealth to overdue pensions, compensation for war victims, ninja training, and administrative reform. 180 182

Motherhood and Medical Cooperation

Tsunade becomes pregnant with Gento's child and later gives birth to Uchiha Xi He, who inherits both Senju and Uchiha bloodlines alongside the Natural Sage talent trait. 158 190 216

She deepens Konoha's institutional cooperation with Hidden Xuan Village, proposing that Konoha's new genin receive training under Uchiha jonin and supporting an expanded medical-ninja training program. 182 191 192

Support for Shinobi World Unification

Although initially reluctant to support another war, Tsunade agrees to help Xuandou unite the shinobi world against the Ōtsutsuki threat. She grants access to Hashirama's remains and accepts the use of Impure World Reincarnation to restore him. 215

Tsunade later commits Konoha to Hidden Mystic's cause. Under her leadership, Konoha formally merges with Hidden Mystic while she remains responsible for its affairs. 313 322

Land of Snow Conflict

Tsunade accompanies Xuandou during the Land of Snow crisis, where she helps investigate the appearance of a ninja resembling Jiraiya. After her Wood Release awakens, she battles Kashin Koji using the Rebirth: Strength of a Hundred Technique. 349 351

Notable Quotes

“Konoha was established by my grandfather, the First Hokage, and it is a home protected by the lives of successive Hokage and countless ninjas. It should not fall into the hands of our generation.” 144

“Heroes are the ninjas who bled on the front lines, the martyrs who sacrificed themselves to protect the village. And you? You are nothing but parasites sucking the blood out of Konoha!” 180

“Konoha will stand behind you and assist you in unifying the entire Shinobi World. To bring the dawn of peace to the Shinobi World!” 313