Scientific research is undoubtedly very expensive.
The scientific research here is real scientific research, not the kind of scientific research that is trying to sell something like a sheep over someone else's head, but a real investment in scientific research.
The investment here is divided into hardware and supporting facilities. The supporting facilities include the treatment of scientific researchers and necessary foreign aid. The hardware is also divided into mechanical equipment and experimental consumables.
Not to mention mechanical equipment, experimental consumables are also ridiculously expensive.
Fei Yang Agriculture We have only purchased experimental mice for the time being. Some varieties are quite cheap, costing hundreds or even thousands of yuan each. Well, this is already considered cheap.
If you look at human-like primates, monkeys, orangutans, you can't buy one in the tens of thousands, and some have sold for hundreds of thousands.
Just conduct an experiment and you won't be able to make up for it, right? Without a sufficient amount of experimental data, it is simply not credible.
If you buy hundreds or thousands of experimental monkeys, it will cost you millions. Coupled with experimental equipment and scientific research personnel salaries, how can we do it without more than 100 million yuan of funds? There are really few domestic companies that can afford it.
Gene Knockout Mice, is the most expensive breed of white mouse for lab girls. The price is nearly 20,000, which is ten to one hundred times that of other mice.
Gene knockout, as the name suggests, means knocking out a specific gene.
"Boss, these mice with knockout ndrg2 gene fragments are being studied by many institutions at home and abroad. It is currently known that the ndrg2 gene is a factor specifically expressed in the somites. It is first expressed in the preprotosomal stage mesoderm and partially overlaps with the expression profile of fgf8. After the somites are segmented, the ndrg2 gene is expressed in the mesoderm cells of the somites. After the somites differentiate for a period of time, the expression of the ndrg2 gene disappears..."
In addition, Doctor Liu Qinghua, who is responsible for animal genetic research, gave a detailed introduction to Zhou Feiyu.
In front of them, Zhou Feiyu has always behaved like a late learner, diligent and eager to learn. Perhaps due to the blessing of the status of "boss", no one in the research room doubted it very much, but were very happy that it finally had a use.
Of course, they were amazed at the rapid progress of boss Zhou Feiyu. They always thought that if Zhou Feiyu had studied biology and genetics before, he would have become a well-known figure in related fields at home and abroad.
Unlike Huang Hongsheng, the doctor who made the introduction this time is a relatively dull and inarticulate person in life, but he is indeed eloquent in the field of genetic research and has a solid theoretical and insightful foundation.
You can tell it by listening to his introduction to the ndrg2 gene.
Of course, for Zhou Feiyu, these are actually not important. What he really needs is some tool people, some tool people who can implement his plan.
Therefore, the people he recruited are not very powerful, but they all have strong execution ability and solid foundation.
These are naturally not enough for outsiders to understand.
So when he listened to the other party's explanation, he listened very carefully, and then looked at the experimental data of some recent experiments done by the other party.
It must be said that the path that domestic and foreign research institutions have taken has gone smoothly again.
From these data, it can also be seen from Zhou Feiyu that ndrg2-/- knockout mice exhibit a series of vertebral homeomorphic transformation defects. Knocking out the ndrg2 gene in osteoblasts or chondrocytes results in similar defects in vertebrae homeotic transition. Overexpression of the ndrg2 gene in osteoblasts and chondrocytes through transgenic mice col1a1-ndrg2 and col2a1-ndrg2, respectively, results in opposite vertebra homeotic transition defects.
At the same time, the ndrg2 gene plays a role upstream of the hoxc8-11 gene in regulating the pattern and properties of the spine, and may also inhibit the bmp/smad signaling pathway.
"Boss, ndrg1/2 double knockout mice do not show superimposed defects in spine characteristics compared to ndrg1 single knockout or ndrg2 single knockout mice. This shows that the ndrg1 gene does not have a redundant role with the ndrg2 gene in the differentiation process of the spine, and there is a complementary relationship between the two... Starting from this gene, it is indeed possible to find a way to treat spine-related diseases."
Liu Qinghua knows that Zhou Feiyu is very concerned about the progress of Gene Knockout Mice's research experiments. At this moment, he is talking about everything he knows.
"Dr. Liu, you did a great job."
Zhou Feiyu nodded, smiled and praised.
He naturally knew that what the other party said was the truth.
He knew better that what the other party was talking about was just the current research results. And in his mind, he has not only the current research results, but also the advanced technology from the galaxy.
Dr. Liu's face immediately showed a happy look and said, "This is what I should do."
"I've been thinking about it for the past few days and came up with some plans to adapt some medicinal materials. Dr. Liu, you can help me verify it and see what the effect is. In addition, you can find a way to induce some Spinal Disc Herniation mice. I can use it."
Zhou Feiyu then talked about other arrangements and handed Liu Qinghua a hard drive while talking.
Liu Qinghua was startled when he heard it, but he quickly reacted and quickly reached out to take the hard drive. "Okay, boss."
He was a little confused, why did Zhou Feiyu suddenly think of Spinal Disc Herniation's disease?
However, as an honest person, he felt that he could just do what his boss told him to do without having to think about other things.
Zhou Feiyu stayed at the Agricultural Research Laboratory until after seven o'clock in the evening before he asked the driver to take him back to Nanjiang County City. During this period, he was either discussing issues with the on-site research institute or looking at data and making suggestions.
When he left, the atmosphere among the researchers suddenly became more relaxed, and there was another discussion about why Zhou Feiyu, who was born in materials science, had such a strong learning ability in biology and genes?
At this time, just after eating and taking a break, the researchers were walking and chatting in twos and threes on the asphalt roadside in the greenhouse area.
Liu Qinghua, an honest man, couldn't help but participate in the discussion, and asked a question that he had been holding back from asking today, "The boss asked me to induce some Spinal Disc Herniation guinea pigs today. What do you think the boss wants to do?"
"What else can this do? I think the boss wants to conquer this lifelong cancer Lumbar Disc Herniation!"
someone answered immediately.
"Haha, you can have this."
Almost no one believes it, because it has been decades or hundreds of years and there is no good treatment for Lumbar Disc Herniation, let alone a cure.
"What are you talking about?"
Huang Hongsheng, as the person in charge of the research room, was just behind them and immediately greeted them loudly after hearing the laughter.
Everyone looked back and saw him, and immediately slowed down.
Someone told them about their discussion.
Huang Hongsheng immediately shook his head, with a helpless and funny look on his face. "You guys, you usually say you want to have a good relationship with your boss, but you don't even know the situation at the boss's home, so why are you talking about building a good relationship? Don't you know that the boss's father has this disease? Not long ago, he was in the hospital for more than a week."
"Huh?"
"So that's it. No wonder the boss is so interested."
"The boss is really a filial son!"
Everyone was surprised.