Tsunade

Biodata

Feature	Details
Name	Tsunade (纲手)
Alias(es)	Lady Tsunade; one of the Konoha Sannin; Fifth Hokage of Konohagakure 59 264
Gender	Female
Affiliation	Konohagakure 56 264
Occupation/Role	Medical Ninja; head of the psychological medical ninja system; Fifth Hokage 60 264
Status	Active 456
First Appearance	Chapter 56

Power Progression

Stage / Realm / Level	Chapter	Notes
Yang Release Chakra Mode	350, 384	Beizawa begins teaching her the mode with full-body activation as the goal. Tsunade later activates it in battle against Utakata, vastly increasing her chakra and physical power. 350 384
Wood Release	455	Awakens Wood Release after consuming a pill made from Kaguya Ōtsutsuki's chakra. 455
Ōtsutsuki dōjutsu and combat abilities	456	Is described as possessing the Rinnegan and an Ōtsutsuki-derived Byakugan, with Yomotsu Hirasaka and Eighty Gods Vacuum Attack among her key abilities. 456

Background & History

Tsunade is the granddaughter of Hashirama Senju, the First Hokage, and a former student of Hiruzen Sarutobi, the Third Hokage. Her lineage, medical reputation, and standing as one of the Konoha Sannin place her among Konohagakure's most prestigious ninja. 62 69

She spent a long period away from the village. Upon returning, she avoided living in the former Senju compound because it carried painful memories, but her return immediately strengthened Konoha's sense of security. 52 60

Appearance

Tsunade is a fair-skinned woman with dazzling blonde hair, brown eyes, and a mature, striking presence. At her first meeting with Beizawa, she wears a tea-green jacket. 59 256

• Blonde hair and fair features. 59
• Brown eyes. 256
• Often wears a tea-green jacket. 59
• Wears the Fifth Hokage's white ceremonial robe during her inauguration. 264

Personality

Tsunade is blunt, impatient with evasiveness, and willing to confront both Hiruzen Sarutobi and Shimura Danzo directly when she believes Konoha's rules or people are being endangered. 134 165

Despite initially resisting involvement in village affairs and preferring to avoid work when possible, she repeatedly assumes responsibility when people close to her need protection. Her decisions to confront Root, rescue Dan Kato, command Konoha's forces, and accept the Hokage position reflect her eventual commitment to the village. 134 165 240 264

She has a persistent gambling habit and exceptionally poor luck, repeatedly losing bets and card games. Shizune frequently tries to prevent her from going to casinos. 86 126 342

Abilities & Skills

Medical Ninjutsu

Tsunade is recognized as the most outstanding Medical Ninja in the Ninja World and leads Konoha's medical development. 60 62

• Examined Yakumo Kurama's dangerous Yin Release condition and began conditioning her body despite its complexity. 60
• Restored and treated Rina Uzumaki after her prolonged exploitation in Kusagakure. 151
• Directed medical research into Kimimaro Kaguya's Bloodline Limit Disease. 308
• Learned Limb Regeneration to help treat injured Konoha ninja. 282
• Can prepare antidotes for hazardous environments. 390

Monster Strength

Tsunade concentrates chakra into overwhelming physical strikes capable of shattering terrain and overpowering powerful opponents. 134 384

• Used Painful Sky Foot to break apart Beizawa's flaming shuriken assault with a single stomp. 134
• Destroyed Kusagakure's Earth Style attacks with Monster Strength during the rescue of Rina and Karin. 151
• Defeated Six-Tails Jinchūriki Utakata through repeated close-range strikes, even breaking through his transformed tails. 384
• Her Monster Strength served as the model for Beizawa's and Kurenai Yūhi's training. 165 250

Yang Release Chakra Mode

Tsunade learns Yang Release Chakra Mode from Beizawa, using it to elevate her chakra and combat capability. 350 384

• The intended end state is full-body activation. 350
• Her activated chakra approaches the level of Utakata's partial Tailed Beast Transformation. 384
• The mode allows her to physically dominate Utakata after he draws on Six-Tails chakra. 384

Wood Release and Ōtsutsuki Powers

After receiving Kaguya Ōtsutsuki's chakra through Beizawa, Tsunade awakens powers beyond her previous medical and taijutsu specialties. 455 456

• Awakens Wood Release. 455
• Possesses the Rinnegan and an Ōtsutsuki-derived Byakugan. 456
• Can use Yomotsu Hirasaka and Eighty Gods Vacuum Attack. 456
• Uses Almighty Push to repel Ōtsutsuki Isshiki's black rods. 456

Shikkotsu Forest Contract

Tsunade is a contractor of Shikkotsu Forest and has access to Katsuyu, the slug Summoning Beast. 223

• Her name appears alongside Hashirama Senju's on the Shikkotsu Forest contract scroll. 223
• Entrusted Beizawa with the contract so he could summon Katsuyu and seek assistance during missions. 223
• Katsuyu can crush enemies with its size and attack using corrosive liquid. 223

Relationships

• Hiruzen Sarutobi — Former teacher and predecessor as Hokage. Hiruzen supports her return, entrusts her with major responsibilities, and formally passes the Hokage hat to her. 60 239 264
• Beizawa — Her medical-ninjutsu student, strategic partner, and later reciprocal teacher. Their relationship begins with a Rasengan wager, develops through joint medical work and warfare, and includes mutual instruction in techniques such as Limb Regeneration and Yang Release Chakra Mode. 86 89 266 350
• Shizune — Her close companion and medical associate. Shizune assists Tsunade's work while repeatedly trying to restrain her gambling. 89 126
• Yakumo Kurama — A patient whose dangerous Kekkei Genkai Tsunade investigates and treats. Yakumo later helps with Tsunade's hemophobia treatment through psychological medical ninjutsu. 60 199 228
• Shimura Danzo — Political adversary. Tsunade openly opposes his Root operations, rescues people targeted by Root, and ultimately weakens his influence in Konoha. 134 165 166
• Katsuyu — Her Shikkotsu Forest summon and a source of support for her allies. 223
• Rina Uzumaki and Karin — Tsunade leads the operation to rescue them from Kusagakure, citing Konoha's alliance with the Uzumaki Clan. 150 151

Story Role

Return to Konohagakure

Tsunade returns to Konoha and immediately requests to see Yakumo Kurama and Beizawa. After examining Yakumo, she agrees to attempt treatment and becomes head of Konoha's new psychological medical ninja system. 56 60

She meets Beizawa as the initiator of the system. Although initially playful toward him, she becomes serious once his medical proposal and Yakumo's condition are discussed. 60

Beizawa's Medical Mentor

After losing a wager over Beizawa's ability to learn the Rasengan in three days, Tsunade accepts him as a medical-ninjutsu student, though she charges for her instruction. 86 89

Beizawa's rapid progress impresses both Tsunade and Shizune. Tsunade recognizes him as a potential medical rival after he learns the Healing Technique in eight hours. 102

Hemophobia Treatment

Tsunade's hemophobia prevents her from fighting at full capacity and becomes a major concern for Hiruzen and Konoha. 126 161

Though initially stubborn about psychological treatment, she agrees to become Beizawa and Yakumo's first patient. Her condition gradually improves through treatment, and she is ultimately cured before Konoha's victory over Kirigakure. 155 199 228 255

Conflict with Root

Tsunade intervenes against Root after learning of its actions against Kabuto Yakushi and Yakushi Nonō. She gains authority to mobilize the Anbu and tests Beizawa before approving his participation in the Kabuto retrieval mission. 134 135

She later leads an Anbu assault on a Root base to rescue Dan Kato, openly defying Danzo. The operation contributes to the disbandment of excess Root members and sharply reduces Danzo's influence. 165 166

Kirigakure War

When Kirigakure declares war on Konoha, Tsunade becomes frontline commander, with Shikaku Nara serving as strategist. Her appointment also strengthens her position as Konoha's leading Hokage candidate. 238 239

She directs the campaign's strategy, assigns Beizawa to lead the supply transport team, and identifies Kirigakure vanguard strongholds as targets for Konoha's counteroffensive. 240

Tsunade and Beizawa defeat Fourth Mizukage Karatachi Yagura, ending the conflict and securing Kirigakure's surrender. 255

Fifth Hokage

After the war, Tsunade accepts Hiruzen's retirement and begins the succession process. 259

She is elected and formally inaugurated as Konohagakure's Fifth Hokage, receiving the Hokage hat from Hiruzen before the Daimyo, Konoha's ninja, and its civilians. 264

As Hokage, she establishes a Medical Ninja class for Limb Regeneration, orders the identification of disabled Konoha ninja for treatment, creates the Hokage Secretary Office, and brings the Uchiha and Hyuga clans into Konoha's high command. 265 274

Later Leadership

Tsunade continues working alongside Beizawa on village reforms, diplomacy, medical advancement, and defense. She supports his plans for economic independence, allows him access to advanced medical techniques, and increasingly prepares him as a future Hokage. 270 291 409

She also personally joins high-level operations, including the capture of Utakata and the relocation of the Tsuchigumo Clan to Konoha for protection. 384

Notable Quotes

“I am Tsunade.” 151

“I will do my best, Teacher.” 264