The Uzumaki Clan were born with Yang Release Chakra, and as masters of Sealing Jutsu, they also possessed excellent Chakra control. As for theory, medical theory and knowledge could hardly be more difficult to learn than the theory behind Sealing Jutsu.
"The Medical Department?" There was no doubt that Sarutobi Hiruzen was tempted.
The Uzumaki Clan had yet to find their proper place in Konoha. After all, Konoha's prominent clans had many interests tied to the village itself.
Take the three Ninja clans of Ino-Shika-Cho, for example. The Yamanaka Clan handled the intelligence division, the Nara Clan often served in the War Council, and the Akimichi Clan were basically assigned to combat units. At the same time, they had businesses in Konoha involving medicinal herbs, food, ornaments, and more. Even without any Will of Fire, they would still keep in step with Konoha for their own interests.
Right now, the Uzumaki Clan lacked such ties of mutual interest in Konoha. The positions best suited for the Uzumaki Clan's Sealing Jutsu were simply too important to hand entirely to a Ninja clan that had only just pledged allegiance.
The Medical Department was different. Though important, it did not involve Konoha's various secrets, nor did it concern the village's very survival. For the current Uzumaki Clan, it was indeed a good destination.
Moreover, Tsunade was powerful, renowned, and possessed one-quarter Uzumaki blood. Subduing the Uzumaki Clan would be effortless for her.
On top of that, Tsunade was a direct and legitimate descendant of Konoha's Hokage line. Sarutobi Hiruzen would be quite at ease entrusting the Uzumaki Clan to her.
As for cultivating confidants and expanding influence, so long as it did not affect Konoha, Sarutobi Hiruzen would not care. Danzo had done far more outrageous things, but in the end, he still