The Real Cheat

Sakura Haruno is currently conducting research on a technique that transforms human cells into stem cells, and then induces these stem cells to differentiate into cardiomyocytes to form the heart.

However, given the time constraints, what she did could hardly be considered "research"; at most, she was simply following the instructions in accordance with the materials.

Konoha actually has its own stem cell technology.

The surgery that previously used Yugao's hair to create a new heart was an application of this technology.

In Sakura's previous world, similar technology had actually been invented long ago. The transformation of keratinized cells from human hair roots into embryonic stem cells was already achieved by humans on Earth in 008. Compared to cloning a complete human, simply dedifferentiating somatic cells into stem cells and then creating human organs is not too difficult.

In this world where magical Chakra exists, the barrier to entry for this technology is even lower; no problem is insurmountable when it comes to Chakra...

However, because Konoha completely halted human experimentation, this technology stagnated. Without a perfected and flawed technology, Yugao's new heart was just a crudely made, inferior product.

Now, thanks to the data obtained from Orochimaru's base, this technology has finally been fully supplemented.

Stem cell research is the most important preliminary technology for cloning projects, so Orochimaru's materials describe in great detail how to dedifferentiate human cells and transform them into embryonic stem cells.

It must be admitted that Orochimaru is indeed a genius! Single-handedly, he elevated the biotechnology of the Hokage world from the equivalent of the 0th century to the level of the 1st century...

Perhaps we should also count the contribution of a person named "Shin". According to the information, this person was a key experimental subject for Orochimaru's cloning technology. His physique was very special, and he would not reject any tissue transplanted into his body.

Of course, the biological knowledge I learned in my previous life also helped a lot.

Although she wasn't a biology student in her previous life, and only learned some rudimentary biological knowledge from textbooks and online resources like Zhihu and Kezi—scientific knowledge can't be faked with fabricated information—she at least had a high-level understanding of the essence of life. Orochimaru painstakingly researched for so many years before finally understanding what genes are, but that was common knowledge she had to learn in high school in her previous life...

No kidding, the knowledge of her past life stored in Sakura's mind is a real cheat code that's more powerful than any external cheat!

Returning to the point, the situation in the Shinobi World is quite similar to that of her ancient homeland in her previous life. Both worlds have advanced science and technology, but their theoretical research is not very in-depth, resulting in a situation where they have skills but lack principles. Perhaps this is because both are overly pragmatic? Moreover, this world has Chakra, so many techniques can function without understanding their principles, and the effects are astonishing. Therefore, ninjas often know how to use Ninjutsu but not why, and they don't feel the need to study the theories in depth...

In short, Sakura Haruno Konoha filled in the gaps in Konoha's stem cell technology. She combined Orochimaru's and Konoha's information with the knowledge she had learned in her previous life and compiled them into a more complete and comprehensive system.

Following the steps in the documentation, Sakura meticulously carried out the experiment.

With the aid of Medical Ninjutsu, the experiment proceeded smoothly and the first few results were quickly obtained.

Evening.

Chakra Sasuke, appeared in the lab carrying a lunchbox and some dishes. "Aunt Xue, you must have forgotten to eat dinner. You asked me to bring you some."

"Oh, is it already lunchtime?" Sakura Haruno looked up blankly, glanced at Sasuke, then looked down again. "Wait a minute, leave it there, I'll be done in a minute!"

Sasuke sighed, walked over and unplugged the microscope, saying firmly, "It's already evening... You haven't had lunch yet, have you, Sakura? Eat first!"

With the light source gone and nothing visible in the microscope, the girl finally stood up, rubbing her eyes unsteadily. "Okay, let's eat first!"

She knew what she meant by "soon," which usually meant waiting for more than an hour...

Because there are no cell phones to distract her in this world, Sakura finds it easy to concentrate on her work. However, she often overdoes it, to the point of forgetting to eat and sleep. Actually, it's just that when she's focused on her work, she forgets the passage of time.

As Sakura Haruno picked up her lunchbox and began to eat her two meals in one, Sasuke walked around her laboratory twice.

"Is this Uzuki Yugao's heart?" the black-haired boy asked, pointing to the several dark red hearts soaking in the orange-yellow liquid in the experimental container.

Sakura Haruno's laboratory was somewhat similar to the human laboratory he had imagined, but the overall tone was completely different.

He always imagined a human experimentation lab to be covered in dark red spots, with bloody, mutilated corpses and chunks of flesh scattered haphazardly on the tables, and the air thick with the stench of decay and rotting flesh—that's exactly what early human experiments looked like. Sakura's lab, however, was clean and tidy, without any unpleasant odor... If he had to pinpoint a smell, he could only detect the faint fragrance of a young girl. If it weren't for the few chunks of heart and flesh floating in the nutrient solution reminding him, Sasuke wouldn't have realized that human experiments were being conducted here.

Sasuke's guess was wrong.

"No, this is my heart..." Sakura Haruno, who was sitting to the side slowly eating her dinner, answered his question.

After swallowing the last bite of food, Sakura wiped her mouth clean and explained, "Sister Yugao doesn't have much living tissue, so we can't waste it. This experiment was done using cells from the Root of my hair."

"It looks pretty good. Did it work?"

"Judging from its appearance, it should be a success... I haven't even tried it yet!" Sakura said, stroking her chin.

"Tried it?" Sasuke raised an eyebrow, glancing at Sakura Haruno. "How did you try it? Do you mean...?"

His gaze swept over Sakura's chest, his unspoken message conveyed without him saying a word.

The girl rolled her Byakugan at him fiercely. "Do you think I'm that stupid to joke around with my own body!"

Of course she wouldn't operate on herself...

Actually, this test is quite simple: just check how much Chakra they can generate. The greater the amount of Chakra, the stronger the heart's vitality.

Sakura walked over, placed her hand on the container wall, and used Medical Ninjutsu to activate the floating heart inside. Soon, it began to beat vigorously.

"Physical power has already been generated... I'll put my mental power into it now, and if the experiment succeeds, new Chakra will be generated in the heart!" she said, staring intently at the heart inside the container.

Then, as Sakura infused her spiritual power into the container, the transformation began...

The shared spiritual and physical powers naturally merged together, forming a formidable Chakra.

Frost flowers silently appeared on the container wall, and the nutrient solution inside the container was frozen into ice in just half a second, expanding and growing larger, cracking and shattering with a crack.

Before she even underwent Nature Transformation, her new heart had already naturally formed Ice Release Chakra!

Sakura Haruno was also taken aback.

Such pure Ice Release Chakra...

Has it become an instinct of the flesh? My DNA... has been completely modified by the Ice Release Kekkei Genkai! Sakura recalled the Sage Katsuyu's prediction, and she now fully understood its meaning— the Ice Release's adjustment to her body had penetrated to the level of the very origin of life.

Therefore, with her current cells dedifferentiating and then redifferentiating to form a heart, it would be a heart completely belonging to Ice Release. Even without manipulating Chakra, it could instinctively begin the Nature Transformation of Ice Release... Sakura quickly realized that this was a heart completely adapted to Ice Release Kekkei Genkai, and if she used it to perform Ice Release, it might be even more powerful than her old heart!

"Such pure Ice Release Chakra!" Sasuke touched the icy shards that emanated a chilling aura and exclaimed in admiration. "However, as a heart, the amount is still not enough. It should be at least half of yours to be considered adequate, right?"

Sakura waved her hand in denial, saying, "No, this new heart hasn't been trained, so its physical strength definitely won't be very high. It's already quite good that it has this much."

The newly formed heart was clearly no match for her heart, which had been tempered and refined over countless trials. The amount of Chakra was roughly equivalent to that of a newly graduated Genin, which was quite remarkable for an untrained heart.

Of course, this is not the most perfect result; there is still room for improvement.

After sealing the heart into a scroll, Sakura tested several other hearts.

There were failures and successes. One went wrong and couldn't be activated at all; it was a dead heart. Several others had various defects and showed no signs of life.

Sakura Haruno meticulously recorded the experimental process of these failed experiments—for experiments, sometimes the experience of failure is more important than the experience of success.

After eliminating the undesirable candidates, four or five who seemed to be performing well were left.

They can all reach a level similar to the first heart, with a considerable amount of Chakra, and are very adapted to Ice Release. There is even one, who is particularly sensitive to Ice Release, and the ice he created almost froze Sasuke reached out to touch it.

Did a new change occur during dedifferentiation?

Unfortunately, with her current level of expertise, she is far from being able to explore the answer to this question.

The wonders of life far exceeded Sakura Haruno's imagination...

Sakura desperately wanted to know how Kekkei Genkai modulated the body, and what changes had occurred in her genes... However, she probably wouldn't have time to explore the answers to these questions for a very, very long time.

All she needs to know right now is that Ice Release is extremely beneficial to her body.

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