Gene

This question was far from simple. As Genomics had developed to this day, the discussions and controversies surrounding it had extended from structural and functional genomics to the evolution of life, then to philosophy, and even to the division of academic resources and political territory. It could make for a very interesting story.

What exists is justified.

That was true.

But did existence mean usefulness? Take our appendix and Wisdom Tooth, for instance. They were not particularly useful and caused no small amount of trouble. More often, they were relics left behind by human evolution, hardly any sort of treasure.

The 98.5% of Non-coding Sequence in the human genome also had to be viewed dialectically.

As early as the 1960s and 1970s, people had begun calling Non-coding Sequence "Junk DNA."

Yet people soon discovered that quite a few Non-coding Sequence were closely related to Gene Transcription Regulation.

Junk was not truly junk, and life was far more than just the Central Dogma.

So what good things did Non-coding Sequence contain? The classic non-coding DNA elements in textbooks included promoters and enhancers, Transposable Element, as well as biologically active Small RNA.

In the early development of Molecular Biology, the exquisitely ingenious biochemical experiments scientists designed to peer into the black box of life truly left later generations in awe!

And in this new century, where High-throughput methods and Big Data reigned supreme, the unquestionable main force in non-coding DNA research was the ENCODE Project.

It was a model of large-scale global scientific collaboration and a pioneer of biological big data.

Dozens of research teams around the world used the latest High-throughput experimental methods to systematically and comprehensively scan the biological activity of all non-coding DNA in various tissues of humans and other organisms.

The methods they used included ChIP-seq, which detected interactions between chromatin and proteins; RNA-seq, which sequenced all RNA molecules in a cell as a whole; DNase-seq, which sequenced regions of chromatin sensitive to DNase—areas with looser, more exposed structures; and so on and so forth.

Unfortunately, CRISPR did not exist at the time. Otherwise, it would have been extremely suitable for testing the functions of genomic regions, whether coding or non-coding (Canver et al., 2017).

Now people had already begun following up on it.

In 2012, the ENCODE Project's research results erupted all at once.

Elizabeth Pennisi, a commentator for Science magazine, summarized it this way: "This week, thirty papers were published in journals such as Nature and Science, pronouncing a death sentence on the theory of Junk DNA. The ENCODE Project has discovered that 80% of the human genome is useful."

Of course, many rebuttals and targeted criticisms appeared afterward. Chang Wei did not dare make a rash judgment because his own knowledge was still insufficient.

What kind of joke was that? For a sage of one era to surpass the accumulated knowledge of an entire civilization and find the ultimate answer—what an absurd fantasy that would be!

Nor did Chang Wei think himself a genius with inspiration comparable to Einstein's. If it came to accumulated knowledge, though, Chang Wei did not lack it.

But he felt that most knowledge might simply gather dust in his mind instead of colliding with other knowledge and sparking flashes of inspiration.

"Jason Greene... his location is Vandenberg Air Force Base, but that's classified military information."

Chang Wei held a struggling man in one hand. It was General Randall, the highest commander of Black Watch!

"General, may I ask if you know where this base is?"

Chang Wei asked with a smile.

"You... you... nuclear bomb..."

General Randall had never expected Chang Wei to suddenly appear and instantly crush his defenses. Black Watch soldiers were like ants he could casually crush before Chang Wei's eyes—and then they really were crushed.

Even Super Soldiers could not withstand a single punch from Chang Wei and were reduced to pieces. What shocked him even more was how Chang Wei knew that name. The doctor? But the doctor had already...

"It is Very difficult to step over an ant without killing it, General."

Chang Wei said.

"The nuclear bomb has already... been activated. You madman..."

General Randall had not been frightened into wetting himself or begging for mercy. After Chang Wei loosened his fingers slightly and allowed him to recover from suffocation, those were his first words.

"Inflating yourself like a pufferfish sometimes only makes you more attractive to predators. Besides, who told you a nuclear bomb could destroy me?"

Chang Wei was somewhat disappointed. He knew the nuclear bomb had already been activated and could not be stopped, but he did not care.

He could now accelerate himself to supersonic speed in a short time through principles of flight similar to those of a jet fighter. And because of his size and his own "material strength," Chang Wei could achieve higher Mach numbers beyond the thermal barrier that fighter jets could not break through.

The speed of a Nuclear Bomb Explosion could not keep up with him, so... what was there to fear?

"I don't want to break my bottom line. After all, I'm not like that virus Alex. If you still refuse to tell me..."

A crimson glow appeared in Chang Wei's eyes.

General Randall wore an expression of one ready to face death.

"Then I can only have Hunter tear you apart and eat you first, and then I'll eat Hunter."

General Randall's eyes widened. No, weren't you supposed to give me a quick death?