Benzodiazepine?

The compound with the code name C01A is a white crystalline powder, insoluble in water, but soluble in organic solvents such as acetone.

According to Old Yan's report and after Shen Qi's identification, the two were certain that the main component of C01A was Benzodiazepine azine.

"Benzodiazepine, Old Yan, you're something else," Shen Qi said.

Well-known Benzodiazepine drugs on the market include Diazepam and Oxazepam. These drugs mainly have several effects: sedation, anti-anxiety, and hypnosis.

"C01A does have value, but not the kind of value I was expecting. But regardless, it's the result of your hard work over the past few months. Compile a complete experimental report and let me take another look." Shen Qi didn't know how to evaluate Old Yan. He had assigned Old Yan to research drugs for anemia, but Lao Yan had produced a product that looked like a combination of sleeping pills and sedatives.

It cannot be said that Old Yan's academic level is lacking. For some reason, he designed a synthetic route that ultimately yielded C01A with a total yield of 22%, which is also a manifestation of his high level of expertise.

Later, Old Tu from next door gave Shen Qi a test report, which was a property analysis of Shen Qi's self-made Le Luo Xian Fen ADME.

In the past few months, Old Tu has conducted numerous experiments on monkeys and mice. The experimental data shows that the skeletal structure of Shen Qi's self-made Le Luo Xian Fen is benzothiophene, with a protein binding rate of over 95%, no CYP involved in metabolism, a half-life of 1.15 days, and a metabolite of glucuronic acid.

Old Tu concluded that Shen Qi's self-made Le Luo Xian Fen could play a certain role in regulating estrogen levels in animals. However, whether it can be equated with the American version of Le Luo Xian Fen still needs time to verify.

To validate a drug, in vivo experiments are necessary, animal experiments are the first step, and the key is clinical trials, since the drug is ultimately used to treat humans.

Shen Qi's center lacked the resources and qualifications to conduct clinical trials, which is why Old Tu reached the above conclusion.

Shen Qi never intended to commission a qualified institution to conduct clinical trials on this experimental product; he just wanted to practice and accumulate pharmaceutical experience and data.

From theoretical research to laboratory preparation, to animal experiments and clinical trials, and finally to obtaining approval from relevant departments and launching a new drug, it is not an easy task.

Shen Qi, Old Yan, and Old Tu can currently only work on animal experiments, developing small batches of chemical test products in the laboratory and accumulating experimental data on animals.

At five o'clock in the afternoon, Shen Qi called Old Yan and they set off for a blind date.

Once downstairs, Old Yan consciously sat in the driver's seat of Shen Qi's Mercedes-Benz SUV. When going out to dinner with a leader, you can't let the leader drive, can you?

Old Yan drove to the entrance of the School of Mathematics and waited with Shen Qi for a while. They saw two women come out of the School of Mathematics building.

One of them, with a bulging belly, was pregnant, and another young woman was helping her.

"Is Dr. Ou your wife? And the short-haired woman next to her, that's her, isn't she?" Old Yan asked.

"Xiao Lian, my wife's best friend." Shen Qi got out of the car, opened the back door, helped Ou Ye into the back seat, then got into the back seat himself, and let Xiao Lian sit in the front passenger seat.

Shen Qi introduced everyone, "Yan Jun, a chemical Engineer at our center. This beautiful lady is Xiao Lian, an assistant researcher at the School of Mathematical Sciences. By the way, Xiao Lian, what's your full name again?"

Xiao Lian: "My full name is Lian Zilu."

"Lotus seed dew?" Old Yan wanted to laugh as soon as he heard that.

"You Old Yan, you always burst out laughing the moment we meet. Is Lianzilu really that funny?" Shen Qi said, "It's a very sweet name. Xiao Lian lives up to her name; she's a sweet girl. Let's go, Old Yan, drive!"

The dining area has a quiet and peaceful environment, suitable for chatting.

Old Yan is 1.75 meters tall, not tall, not fair-skinned, and not particularly handsome. His fingers are yellow, a result of long-term smoking.

Xiao Lian is 1.58 meters tall, slightly chubby, and a bit fair -Old Yan didn't give her a stunning feeling; he was just an ordinary engineering student.

Shen Qi subtly pointed out that stories like Cinderella marrying Prince Charming or a working-class man marrying a rich and beautiful woman are artistic interpretations that transcend reality.

In reality, most marriages are between equals, where the life experiences, social status, and family backgrounds of both spouses are roughly equivalent, which is essential for a long and stable marriage.

Shen Qi felt he had done his best as matchmaker; whether it was meant to be or not was up to Old Yan and Xiao Lian to decide.

"We had a very pleasant chat today. Well then, Yan Gong, why don't you take a taxi later to send Xiao Lian home? You two can then continue with the second half of the event and get to know each other better. Ou Ye and I will head out first; I've already paid the bill. Have a great time." Shen Qi and his wife left early, leaving Old Yan and Xiao Lian alone.

Back at the academician's villa, Ou Ye said, "Actually, every girl dreams of her Prince Charming."

Shen Qi: "But history tells us that princes almost always married daughters of noble families."

Ou Ye: "Can you not be so realistic?"

"Ordinary girls aren't necessarily happy with princes," Shen Qi said.

"Yan Jun is nothing special." As soon as Ou Ye got home, she rejected the Old Yan that Shen Qi had so earnestly recommended.

"Whether they have any special qualities or not isn't up to you to decide, it's up to Xiao Lian. I think they're a good match; I have a better eye for people than you do. Okay, you should get some rest; I'll do some research and then go to sleep." Shen Qi helped Ou Ye upstairs to the bedroom.

"Are you planning Mathematical Grand Unification?" Ou Ye asked.

"The project has already been approved," Shen Qi said.

Ou Ye asked with great interest, "Who are the members of the project team?"

"I am Li Zhenqiang, and it's just the two of us right now."

"Li Zhenqiang's major is Algebraic Geometry, so who's doing number theory?"

Shen Qi patted his chest. "Your husband is me."

"You?" Ou Ye pinched Shen Qi's ear, asking with increasing curiosity, "How far have you progressed in the number theory section?"

Shen Qi humbly replied, "I haven't started yet because my skills are limited. I've encountered many difficulties in the initial stages of advancing the number theory section. After you give birth, I will specifically consult with Dr. Ou, a number theory expert, on related issues. But right now, Dr. Ou's main task is to focus on the pregnancy."

"Good boy." Ou Ye patted Shen Qi's head, then touched her own belly. The husband and child in front of her and inside her were her most important family members.

Mathematics was another source of inspiration for Ou Ye, but there will always be a period in a woman's life when she cannot concentrate all her energy on her favorite pursuits.

A few days later, Old Yan handed Shen Qi a chemical experiment report. The report detailed the molecular design, synthetic route design, products and yields of each step, crystal preparation, and other experimental processes of C01A. The conclusion was that Old Yan had synthesized a new compound, but its specific uses remained to be verified.

This is a chemistry paper. Old Yan majored in chemistry and knows some medicinal chemistry, but he is not a pharmacologist or a medical scientist.

The writing style of pharmaceutical papers differs greatly from that of Old Yan's chemistry paper. Pharmaceutical papers do not describe many specific processes of drug preparation. Pharmacists and medical scientists focus more on research findings in professional fields such as drug resistance monitoring, clinical studies, pharmacokinetics, and bioequivalence (BE).

As for the specific uses of C01A and whether it has scientific research value, that is something Shen Qi needs to determine.