The Active Compound
After a day and a night of intense work, cheers erupted in the laboratory. "We made it!"
A new compound was discovered, and the next step was various tests.
Chemical structure testing data shows that this is an Eight-membered heterocyclic compound.
"Director Shen, let's name this Eight-membered heterocyclic compound," Cao Fan said excitedly and expectantly as he grew up.
Naming new compounds is a basic task, and anyone in this lab is proficient in using more than three internationally accepted naming rules.
For a period of time, He Lin, Cao Fan, and their group were working on Seven-membered heterocyclic compound.
They used compounds a, b, c... z to label these Seven-membered heterocyclic compound. When they ran out of English letters, they continued to use a combination of English letters and Arabia.
In this project, compounds with octet or less do not deserve formal chemical names because they are all process products.
Of course, these process byproducts are also meaningful; without the process, how can there be a result?
The newly discovered Eight-membered heterocyclic compound is different; it requires activity testing. If the activity test is passed, the next step is to synthesize the drug.
Once the drug is developed and passes several phases of clinical trials, then the project is considered a success.
If the LPJK1 project succeeds, it will not only be a victory for drug synthesis, but also a victory for basic theoretical research.
The comprehensive victory of combining academic research with engineering applications has yielded a result that is more valuable than building a seven-story pagoda: saving a life.
At such a significant moment, when it came to naming the first Eight-membered heterocyclic compound, the public unanimously suggested that Shen Qi be in charge.
"Then I will respectfully accept your offer." Shen Qi clasped his hands together in gratitude, thanking everyone for their hard work.
There are several naming principles for heterocyclic compounds internationally, Shen Qi decided to adopt the Hansi-Wiedemann heterocyclic system of nomenclature.
In this naming system, unsaturated rings with the largest number of non-cumulative double bonds are generally named as suffixes. Rings with three to ten members correspond to the heavenly stems of A, B, C, D, W, He, Geng, Xin, Rengui, and those with more than ten members are eleven, twelve...
Based on the Hansi-Wiedemann heterocyclic nomenclature system, Shen Qi quickly provided the name: "1,3,4-Triazaoctyl ring. Thank you all for your hard work. Now, let's do the activity test."
A chemistry student's daily life consists of one experiment after another, one test after another.
Patriotism, dedication, integrity, and friendliness.
Since I've chosen this profession, I'll stick with it until the end of time.
Activity testing involves selecting specific cells to process into test cell lines, and then performing specific activity tests on the synthesized compounds.
If the activity test results are satisfactory, then the Active compound can proceed to the animal testing phase.
If it's not okay, then the earlier statement that "saving a life is better than building a seven-story pagoda" is just empty talk.
Activity testing of compound 1,3,4-triazaoctyl ring is underway.
The lab technicians perked up and conducted the tests.
"OK! Activity test OK!"
Great news! The LPJK1 project has finally produced an Active compound.
But one Active compound is far from enough. What if it fails animal testing?
Therefore, it is important to have several Active compound in stock.
For a drug project, small pharmaceutical companies typically prepare two or three Active compound, while large pharmaceutical companies generally have more than 20 in reserve. Pharmaceutical giants like GLK often prepare sixty or seventy Active compound.
Active compound that have passed animal testing have market value. If they pass Phase I clinical trials, their value will increase further.
Most small pharmaceutical companies do not develop new drugs. After obtaining the Active compound and passing animal experiments or Phase I clinical trials, they sell it to large pharmaceutical companies.
Phase II and Phase III clinical trials are too expensive; small pharmaceutical companies simply can't afford them.
The patent development rights for LPJK1 have been sold to Ou Beiqi Pharmaceutical, Ou Beiqi Pharmaceutical model involves factories working in conjunction with laboratories.
Whatever Shen Qi's lab provides to Ou Beiqi Pharmaceutical will produce that product.
"Let's continue working on Active compound, specifically 1,3,4-triazaoctyl ring derivatives." Shen Qi led everyone to continue their efforts, accumulating resources and producing more Active compound.
On Monday.
The Chemistry Laboratory at Shen Qi Research Center has achieved another breakthrough. "Success! Success! Derivative 1 of 1,3,4-triazaoctyl ring has been synthesized!"
"OK, OK! The activity test results for 1,3,4-triazaoctyl ring derivative 1 are very good!"
Tuesday.
The Chemistry Laboratory at Shen Qi Research Center was jubilant. "We've got it! We've synthesized derivative 2 of the 1,3,4-triazaoctyl ring!"
"No problem, no problem! The activity test results for 1,3,4-triazaoctyl ring derivative 2 are fine!"
Wednesday.
"Damn, what a failure, a complete failure!"
Thursday.
"Wow, that's amazing! The activity test for the Third derivative is excellent!"
Friday, like Thursday, will be omitted.
I worked overtime on Saturday, and the result was similar to Wednesday's: failure.
I continued working overtime on Sunday, and the result was just as bad as Friday's, so I'll skip the details.
Including 1,3,4-triazaoctyl ring, the Chemistry Laboratory of Shen Qi Research Center produced 6 Active compound that passed the activity test within a week.
In other words, Shen Qi and his group produce an average of one Active compound per day.
This efficiency is absolutely terrifying.
The terror continues.
Under the leadership of a multi-award-winning, leading mathematician and physicist, the Chemistry Laboratory at Shen Qi Research Center produced 22 Active compound within a month.
Compared to the laboratories of large pharmaceutical companies, Shen Qi's laboratory is several times more efficient and has a higher success rate.
The LPJK1 project is currently under a high level of secrecy.
During this sensitive period, Miss Walker. Lucy Walker from GLK Company visited Shen Qi under the pretext of academic exchange.
Shen Qi got to know Lucy because of the last visit of the British academic delegation to China.
The British academic delegation has long since returned to Britain, while Miss Lucy remained in China, where she is now the business manager of GLK's China headquarters.
In short, the last visit of the British academic delegation to China was very successful. The two sides reached a high degree of consensus on many academic research projects and engineering application projects, and will carry out specific cooperation in various fields in the future.
Shen Qi received the British delegation with great friendliness and exceptional professionalism, earning high praise and deep recognition from the British side. The British side expressed sincere gratitude to the Chinese Foreign Ministry and expressed its heartfelt hope that the Chinese academic delegation could visit the UK soon.
In light of Shen Qi's outstanding performance in the diplomatic field, the state has plans to arrange for Shen Qi to continue receiving academic delegations from France, Sweden, and Japan.
Shen Qi greeted Miss Lucy, who had come to visit, at the central coffee shop. He glanced at his watch and said, "Lucy, I only have ten minutes. Please get to the point."
Lucy made a helpless and dissatisfied expression, thinking to herself, "Professor Shen, you've changed."