Can, Cannot

After careful consideration, Shen Qi respected the ethics committee's decision that the Phase I Clinical Trial of Triazatrisiloxanes would select only patients with R-type Anemia as subjects.

The next step was to recruit R-type Anemia patients as trial subjects. Professor Qu had some resources, and he quickly recruited a group of R-type Anemia patients. Then came another round of informed consent signing and ethics committee review.

Ou Ye had a general understanding of the research projects Shen Qi was working on.

That night, before falling asleep, Ou Ye said to Shen Qi in bed, "Qi, please include me in the Phase I Clinical Trial of Triazatrisiloxanes."

Shen Qi objected. "I'll give it to you after the drug is successfully launched on the market."

"That would be several years from now, wouldn't it?" Ou Ye demonstrated a resolute determination to seize every minute and face any danger, saying, "I'm also a patient, and I want to participate in the clinical trial."

"Triazatrisiloxanes is a new drug, and it carries risks." Shen Qi didn't need to explain much; he believed that Ou Ye should also be aware of the risks associated with new drugs.

A drug clinical trial is an experiment, and the new drug selected is the experimental product.

Since it's an experimental product, there are bound to be some risks involved.

Ou Ye persisted in her idea. "Qi, let's use me as a test subject. I'm a qualified sample with twenty years of medication experience, making me particularly suitable for tolerance testing."

"No! I absolutely cannot use my wife for human experimentation!"

"Sure."

"Don't want!"

"Or you want it?"

"Little Yezi, don't force me to resort to domestic violence."

Come on.

"I... Mwah!"

"Mwah... So Qi, you agree?"

"Little Yezi, I understand what you're thinking; you want to get better quickly. But let me explain the purpose of the Phase I clinical trial to you..."

Phase I Clinical Trial are the initial stage of human trials for new drugs. From animals to humans, due to species differences, although animal toxicity test results are of important reference value, the drug's response in humans is usually different from that in animals.

Phase I Clinical Trial mainly include human tolerability testing and human pharmacokinetic testing.

Tolerance testing specifically includes observing adverse reactions, the relationship between dose and the occurrence of adverse reactions, and the relationship between abnormal laboratory indicators and dose, etc., in order to obtain the dose range that the human body can tolerate for the new drug, providing important reference data for subsequent pharmacokinetic tests and Phase I Clinical Trial.

Ou Ye herself said that she can conduct tolerance tests and that she has some understanding of clinical trials.

After the tolerability test is completed, a pharmacokinetic/pharmacodynamic test will be conducted in the Phase I Clinical Trial.

Ou Ye's idea was actually very simple: what if I was cured in the Phase I Clinical Trial?

Although Phase I Clinical Trial carry risks, patients with the target disease are the first group to be exposed to the new drug, which can be understood as the world's first group to receive this new drug treatment.

It could take anywhere from a few years to more than a decade for a new drug to pass Phase II, III, and IV clinical trials and eliminate all risks.

Ou Ye didn't want to wait any longer; she worried that if she just kept waiting, she might have to wait until the day she went through menopause.

Therefore, Ou Ye resolutely took a bold step, desperately wanting to participate in clinical trials and gain firsthand access to the new drug. There were risks, but also hope.

Shen Qi didn't sleep well all night; he thought about many, many things.

After daybreak, Shen Qi approved his wife's application. "I'll send you to the clinical trial group."

Throughout the history of medicine and pharmacology, there have been Great Scientist, or madmen, who conducted human experiments on their own bodies.

Yet no one has ever used their spouse for human experimentation.

Shen Qi was the first.

The trust and mutual support between husband and wife are all in the experiment, all in the medicine.

Is my wife alive or dead? Is she recovering or getting worse?

Will they grow old together, or will he remain a widower?

It depends on Shen Qi's research capabilities.

"I really need to level up my chemistry and biology as soon as possible..." Shen Qi's chemistry was level 13 and his biology was level 12. His biochemistry was at the master level.

But Shen Qi was still a little uneasy. What if something went wrong during his wife's clinical trial? Of course, the higher the level of biochemistry, the greater the possibility, efficiency, and accuracy in solving the problem.

The academic achievement points are sufficient.

To advance from Chemistry level 13 to 14, and from Biology level 12 to 13, you need to complete a task.

"Let's finish the chemistry task first..." Shen Qi had actually completed more than half of his chemistry advancement to level 14 task, just one step away from completion.

Big Mathematics Department, Yenching University.

Ou Ye is currently arranging the handover of her work.

In principle, subjects in clinical trials should be admitted to a hospital to facilitate the work of clinical trial medical staff and to better ensure the effectiveness of the clinical trials.

Ou Ye is about to be admitted to the observation ward of Yanjing University People's Hospital, where she may stay for three to five months, or even a year.

First, she had to ask the leaders of the mathematics department for sick leave, which she took for six months.

"Xiao Ou, you're going to be hospitalized? Your health is important, so I approve your sick leave application. Hang in there, I hope you get better soon." The dean of the mathematics department had no objections and approved Ou Ye's leave request.

There wasn't much to hand over in terms of work. Ou Ye was doing an independent research project that she funded herself, and she didn't even write a project proposal.

"Sister Yezi, are you going to be hospitalized? When are you coming back?" Zhao Tian, Xiao Yun, Zeng Han, three Mathematics Department students, asked with great concern.

"I've taken a six-month leave of absence. I hope I can come back within six months. The three of you, don't stop working on the BSD Conjecture." Ou Ye's biggest concern is the BSD Conjecture. They've been working on this project for a while now and have made some progress.

Although concerned about the BSD Conjecture, Ou Ye has come to realize that health is the foundation of everything and the guarantee of scientific research.

The three students looked worried. They were primarily concerned about Sister Yezi's health, and secondly, they felt sorry for the BSD Conjecture.

Without Sister Yezi here, the BSD Conjecture can't continue.

Working on a math project is a continuous process; if you stop updating it for six months, it's likely to fizzle out.

If you want to continue after six months, firstly, the lack of continuity in thinking leads to low efficiency, and secondly, the team's morale will also be affected.

However, Ou Ye disagreed. "I'm in the hospital, not in jail. We can contact each other anytime. What the three of you need to do is calculate the Group Theory model. As for how to calculate it, I've already explained it to you. Do you need me to explain it again?"

Zhao Tian said, "The three of us have already mastered the principles and methods of Group Theory model calculation that Sister Yezi taught us. In fact, we calculated the preliminary results of the group structure yesterday and were just about to have Sister Yezi them when you told us that you need to be hospitalized for half a year... Of course, Sister Yezi's health is always our top priority!"

"Oh, really? You've figured it out? Send the editable version of the file to my email, I'll take a look. Thanks everyone, I'm off." Ou Ye waved goodbye to the three students and embarked on her hospital stay.