Arc 1The Uchiha Crisis
Utsusemi built close ties with the Senju and Uchiha while using her powers and skills to aid both clans. After she treated Izuna’s spatially damaged wound, his condition suddenly deteriorated, and Utsusemi raced to the Uchiha compound to save him.
- Utsusemi saved young Itama Senju through a contract that advanced time outside the Spacetime Tower by ten years, then healed him and left the tower with new powers.
- At Butsuma Senju’s mourning hall, Hashirama and Tobirama recognized Itama and learned Utsusemi had kept him near death outside time until she could release him.
- Utsusemi settled near the Senju, traded goods, built a house with Hashirama’s help, and began training with Hashirama and Tobirama while struggling to control her abilities.
- Utsusemi grew close to the Senju brothers, helped Tobirama refine Flying Thunder God, and used her medical skills to treat Uchiha patients after Izuna and Madara encountered her.
- Utsusemi discovered a shared curse draining Madara and Izuna, treated the brothers, and later harvested crops with Itama and the Senju before agreeing to trade seeds for Ninjutsu manuals.
- As war approached, Utsusemi and Itama made and delivered six thousand portable Military Rations Pills to Tobirama, then traveled to the Land of Hot Water to aid refugees.
- Tobirama fought Izuna, who retreated with Madara after being wounded, and Utsusemi treated civilians and later used medicine to stabilize Izuna’s spatially damaged wound.
- When Izuna’s wound reopened and Yin Release chakra ravaged his pathways, he gave Madara his Mangekyō Sharingan, and Utsusemi raced to the Uchiha compound after learning he might die before dawn.