As for poor robot Isaac being isolated, bullied, and subjected to the silent treatment, Captain Ed had ultimately stubbornly rejected Annie's various reasonable and unreasonable suggestions time and again. He had no intention of letting Annie get involved, merely saying that he would handle it properly himself?
But the result...
Even after poor robot Isaac could no longer endure the bullying and isolation and chose to self-destruct, burning out its own CPU, useless old Uncle Captain Ed still hadn't properly handled its relationship with the rest of the crew aboard the Orville.
Even later, after Uncle John, who claimed to have the smartest brain, found a way to locate Isaac again and activate its backup, he still had no intention of dealing with the matter seriously. He merely said to leave the problem to time, hoping to let the crew grow accustomed to Isaac's presence and gradually, naturally, accept it?
Annie naturally didn't believe such grand-sounding excuses that clearly amounted to laziness and helplessness!
So, feeling rather annoyed after having several ideas rejected one after another, she lost her temper, fell out with those bad uncles again, and hid in her exclusive Number One Simulation Entertainment Room for several days in a row, playing by herself.
Even when the Orville went to pick up some rotten old lieutenant general, successfully negotiated with the Quill people who couldn't stand the light, and obtained permission to explore a mysterious region of space called the Nacraf Zone, she still had no intention of paying them any attention.
In fact, even when the Orville entered the Shadow Realm, which even the Quill people feared, entered that so-called "Gateway to Hell" and "Demon's Abode" in the Khala Sector, encountered something strange that looked like a space station, and then tried to invite Annie along on