The future Fourth Hokage—Uchiha Yue's friend, Minato Namikaze—had all but secured his standing in Konoha.
There were many reasons why Minato Namikaze could secure the position of Fourth Hokage in the future, but the most important was that Uchiha Yue, along with Orochimaru, Tsunade, Jiraiya, and the others, had all left Konoha.
If Orochimaru, Tsunade, and Jiraiya—the Sannin who had once shaken the Shinobi World—had not left Konoha, then it would have been utterly impossible for Minato Namikaze to become Hokage. Setting aside the Sannin's prestige within Konoha, the influence wielded by Orochimaru, Tsunade, and Jiraiya alone was beyond anything Minato Namikaze could rival.
It had been somewhat better when Uchiha Yue was still in Konoha. Uchiha Yue and the entire Uchiha Clan had supported Minato Namikaze, wanting him to attain the position of Hokage. But after Uchiha Yue left Konoha, who was there to help Minato Namikaze within the village? Was he supposed to rely on Hatake Kakashi's Hatake Clan to help him become Hokage?
That was simply impossible!
Ever since Konoha's White Fang died, the Hatake Clan had never had any chance of revival. Hatake Kakashi's gradual decline only made it even more impossible for the Hatake Clan to turn things around. Thus, with Orochimaru, Tsunade, and Jiraiya—the Sannin—still in Konoha, Minato Namikaze would have struggled even to rise to prominence, let alone become Hokage.
But who could have imagined that even after Shimura Danzō was killed by Uchiha Yue, Orochimaru would still defect?
Uchiha Yue could understand Tsunade's departure. She had been heartbroken and wanted to leave the place that had caused her such pain. Back then, in order to keep Tsunade in Konoha, the Third Hokage had deliberately found her a fine disciple: Uchiha Yue. Without Uchiha Yue, Tsunade might have long since left that shinobi