Tsunade

Biodata

Feature	Details
Name	Tsunade (纲手)
Alias(es)	Princess Tsunade; one of the Legendary Sannin; “Legendary Fat Sheep”; Fifth Hokage
Species/Race	Human; Senju Clan descendant
Gender	Female
Affiliation	Konohagakure — formerly associated with the village, but initially disassociated from its affairs 18; later serves as the Fifth Hokage 58
Occupation/Role	Fifth Hokage; medical ninja; healer and combatant
Status	Active 265 328
First Appearance	Chapter 18

Power Progression

Stage / Realm / Level	Chapter	Notes
Increased physical strength and vitality	43	Her strength is stated to have at least doubled, with greater monstrous strength and vitality. 43
Wood Release inheritance revealed	108	Uchiha Feng states that Tsunade inherited Hashirama Senju’s Wood Release Kekkei Genkai. 108
Sage Mode	112	Using a senjutsu bracelet supplied with chakra connected to Feng, Tsunade enters Sage Mode; her strength, speed, perception, and overall power increase by more than tenfold. 112
Susanoo Sage / peak Super Kage level	114	While in Sage Mode and wearing Feng’s black-and-white Susanoo Armor, Tsunade’s power reaches the peak of the Super Kage level. 114
Power Fruit enhancement	265	After consuming a Power Fruit, she gains greatly increased chakra and physical power, aerial mobility, and enough force to destroy a mountain with a chakra wave. 265
Kaguya-comparable combat power	271	Following her growth as a Sage Body wielder and Power Fruit consumer, Tsunade is stated to possess strength sufficient to contend with Kaguya Ōtsutsuki. 271

Background / History

Tsunade is a Senju descendant and, following the death of her younger brother Nawaki, is described by Uchiha Feng as the only remaining inheritor of Hashirama Senju’s direct bloodline. 26 This status changes when Feng later revives Nawaki in a living body. 147

She has longstanding ties to Jiraiya, Orochimaru, Hiruzen Sarutobi, and Konoha. However, when Feng first seeks her help, she refuses involvement in anything connected to Konoha, reflecting her estrangement from the village. 18

Feng later presents Tsunade with Root intelligence alleging that her former lover, Kato Dan, had been assigned to approach and deceive her, and that Danzō intended his death to leave her emotionally broken. The revelation drives her into a rage against Hiruzen. 26

After years travelling with Feng, Tsunade returns to Konoha following Hiruzen’s death and accepts the position of Fifth Hokage. She immediately appoints Feng as her assistant despite the objections of Konoha’s advisors. 56 58

Tsunade and Feng later establish a family together. During her pregnancy, Feng revives Hashirama, Tobirama, Hiruzen, and Minato in living bodies so that Konoha’s affairs can be handled while she rests. 158 Their daughter, Qianyu Xi, is born with a Three-Tomoe Sharingan and carries a surname intended to symbolize the union of the Senju and Uchiha clans. 149 178

Appearance

Tsunade has long golden hair and usually wears a dark green robe marked with the character for “Gamble” on its back. 18

• Tall, imposing presence with powerful chakra. 18
• Carries a green pendant, which she later gives to Uchiha Feng. 47
• Her appearance and bearing are widely associated with her status as a Legendary Sannin. 18
• She wears a black bracelet that supplies senjutsu chakra when she enters Sage Mode. 112
• In her Sage-enhanced battle form, she can be clad in Feng’s black-and-white Susanoo Armor. 114

Personality

Tsunade is intensely competitive, particularly when gambling or challenged directly. Although she loses all 100 rounds of Feng’s rock-paper-scissors wager, she accepts the result honorably and agrees to hear his request. 19

She is hot-tempered and physically forceful, readily confronting Jiraiya, Hiruzen, and Feng when angered. 26 27 50 Her anger toward Konoha is rooted in personal loss and suspicion surrounding the decline of the Senju Clan, Nawaki’s death, and Kato Dan’s alleged deception. 26

Despite her volatility, Tsunade takes her work as a doctor seriously. She examines Itachi thoroughly, works toward a treatment for his Bloodline Disease, and insists on monitoring Feng’s health after his near-fatal evolution. 20 37 41

Tsunade also suffers from severe hemophobia; the sight of Feng covered in blood initially leaves her unable to compose herself. 36

As Hokage, Tsunade is decisive and fiercely protective of Konoha. She prioritizes civilian safety during the Eight-Tails’ rampage, confronts Akatsuki directly, and refuses to tolerate disrespect or infighting among the Five Kage. 74 77 143

Tsunade is deeply devoted to Feng and their daughter. Her protectiveness extends to Qianyu Xi, whom she refuses to let Orochimaru study, and she remains determined to find Feng herself when he is believed lost. 178 190

Abilities & Skills

Medical Ninjutsu

Tsunade is regarded as the strongest medical ninja in the shinobi world. 20

• Diagnosed Uchiha Itachi with congenital heart disease and a rare Bloodline Disease. 20
• Identified Sharingan and Mangekyō Sharingan use as a cause of Itachi’s worsening eyesight. 20
• Developed medicine intended to treat Itachi’s Bloodline Disease, though treatment may require up to ten years. 41
• Takes responsibility for monitoring Feng’s condition through regular blood draws after his evolution crisis. 37 41
• Uses Katsuyu to heal and protect civilians during Konoha’s Eight-Tails crisis. 74

Chakra-Enhanced Strength

Tsunade possesses extraordinary physical strength, described as capable of breaking through Susanoo defenses with her bare hands. 17

• Her punch can crater the ground with a single blow. 50
• Her monstrous strength and vitality increase significantly by Chapter 43. 43
• She can keep pace with Feng during their high-speed journey toward the Land of Lightning. 46
• She stops the Eight-Tails’ Tailed Beast Ball assault by striking the transformed beast with a single devastating punch. 77
• After consuming a Power Fruit, she can destroy a mountain with an emitted chakra wave. 265

Sage Mode

Tsunade can enter Sage Mode through a black bracelet that provides her with senjutsu chakra connected to Feng. 112

• Her Sage Mode increases her strength, speed, perception, and overall combat ability by more than tenfold. 112
• She can move through the air while using this enhanced form. 112 265
• Her Sage Mode power is sufficient to terrify Ōtsutsuki invaders and rally Konoha’s defenders. 246
• Her later Sage Body and Power Fruit-enhanced strength are stated to be capable of contending with Kaguya Ōtsutsuki. 271

Susanoo Sage Armor

Tsunade can fight while protected by Susanoo Armor supplied by Uchiha Feng. 114

• The armor combines Feng’s black Susanoo chakra with Tsunade’s white senjutsu energy. 114
• This fusion raises her power to the peak of the Super Kage level. 114
• In this form, she is able to pressure and strike fear into Rinnegan-wielding Uzumaki Feng during Akatsuki’s assault on Konoha. 114 115

Wood Release

Tsunade is stated to have inherited Hashirama Senju’s Wood Release Kekkei Genkai. 108

• Her family’s Wood Release Scroll contains Hashirama’s Wood Release techniques and is regarded as a precious Senju legacy. 43
• Her Senju heritage and later Sage Body contribute to her exceptional vitality and combat potential. 271

Summoning Jutsu

Tsunade can summon a massive slug from Slug Forest. 48

• Summons the slug during the attack on Hidden Cloud Village. 48
• Uses the summon as support while accompanying Feng on his operation. 48
• Summons Katsuyu during the Eight-Tails’ rampage and orders it to heal and protect every nearby civilian. 74

Blood-Based Monitoring

Tsunade repeatedly draws Feng’s blood under the stated justification of medical monitoring. 37 41

• Her visits become far more frequent than the originally proposed monthly schedule, exceeding twenty blood draws in one year. 41
• She later uses her first requested favor from Feng to bite him and drink his blood. 41 42
• Her blood-drinking behavior later escalates into a frenzied episode in which she nearly drains Feng before he can awaken his power. 120

Equipment / Items

• Green pendant — Given to Uchiha Feng by Tsunade; she explicitly warns him not to sell it. 47
• Wood Release Scroll — A precious family legacy containing Hashirama’s Wood Release techniques; it is stolen from Tsunade’s home along with a large sum of money. 43
• Ten-billion-ryō banknote — Treated by Tsunade as her remaining gambling capital. 46
• Senjutsu bracelet — A black bracelet that supplies her with senjutsu chakra and enables her Sage Mode. 112
• Power Fruit — Consumed by Tsunade to dramatically increase her physical power, chakra output, and mobility. 265

Relationships

• Uchiha Feng — Initially his reluctant medical contact after he defeats her in a wager; she agrees to treat Itachi in exchange for three future requests. Their relationship grows increasingly intimate, culminating in Tsunade’s confession and kiss. 19 41 47 They later become husband and wife, raise Qianyu Xi together, and fight side by side in Konoha’s defense and against the Ōtsutsuki. 149 236 272
• Uchiha Itachi — Patient of Tsunade; she diagnoses his illnesses and works to develop a treatment for his Bloodline Disease. 20 35
• Jiraiya — Former teammate and longtime acquaintance. Their reunion is awkward, and they later clash when Tsunade moves to attack Hiruzen. 18 26 27 He later asks her to return as Fifth Hokage following Hiruzen’s death. 57 58
• Shizune — Disciple and travelling companion. Shizune worries over Tsunade’s gambling, assists during medical matters, and obeys Tsunade’s orders during the Hidden Cloud mission. 18 36 45
• Nawaki — Tsunade’s younger brother, whose death deeply affected her. Feng later revives him in a living body, restoring their sibling bond. 26 47 147
• Kato Dan — Tsunade’s former lover. Root intelligence given to her by Feng alleges that Kato’s mission involved deceiving her. 26
• Hiruzen Sarutobi — Her former teacher. Tsunade becomes hostile toward him after hearing Feng’s accusations regarding the Senju Clan and Kato Dan. 26 27 Feng later resurrects Hiruzen alongside the other previous Hokage. 158
• Hashirama Senju — Tsunade’s grandfather and the First Hokage. His Wood Release legacy is important to Tsunade, and he is later resurrected by Feng to help oversee Konoha during her pregnancy. 43 158
• Tobirama Senju — Tsunade’s granduncle and the Second Hokage. She mediates between Tobirama and Feng when his hostility toward the Uchiha Clan resurfaces. 158 232
• Qianyu Xi — Tsunade and Feng’s daughter. Qianyu Xi is born with a Three-Tomoe Sharingan, and Tsunade is fiercely protective of her future and safety. 149 178 236
• Sakura Haruno — Tsunade’s prospective apprentice and mentee. Tsunade encourages Sakura to train until she can stand alongside Sasuke and Naruto. 97 254
• Parallel-world Tsunade — A distinct counterpart encountered through the parallel Shinobi World. Feng explicitly recognizes that this Tsunade is not his wife, while the counterpart later offers Qianyu Xi a place to stay. 200 322 328

Story Role / Major Arcs

Search for a Cure for Itachi

Feng seeks out Tsunade because he believes only the greatest medical ninja can treat Itachi’s worsening condition. Tsunade initially refuses any Konoha-related request, but accepts a wager after Feng challenges her. 12 18

After losing 100 consecutive rounds of rock-paper-scissors, she examines Itachi and diagnoses both congenital heart disease and Bloodline Disease. 19 20

Konoha’s Darkness

Tsunade witnesses Feng’s confrontation with Hiruzen and becomes interested when he claims to know why the Senju Clan declined. 25

After receiving Root intelligence about Nawaki and Kato Dan, she attempts to attack Hiruzen before Feng restrains her. 26 She later flees with Jiraiya when Feng’s Thunderfire Clone destroys the Hokage Building. 27

Feng’s Evolution Crisis

When Feng’s evolution leaves him critically injured, Itachi begs Tsunade to intervene. Though initially doubtful, she agrees to examine him. 35

Tsunade struggles with hemophobia upon seeing Feng covered in blood, but remains involved in his recovery and establishes ongoing health monitoring. 36 37

Growing Bond with Feng

Over the following year, Tsunade repeatedly visits Feng, draws his blood, and brings medicine for Itachi. 41 Her behavior becomes increasingly possessive after she uses one of her three requests to drink Feng’s blood. 41 42

She later gives Feng her pendant, confesses her feelings, and kisses him after he declares his intention to revive Nawaki. 47

Hidden Cloud Village Mission

Tsunade insists on accompanying Feng to Hidden Cloud Village after learning he intends to rescue Uchiha Haruka. 45

She keeps pace with Feng, rides his Nine-Tailed Immortal Fox, and summons a giant slug after they descend into the village. 46 48

Fifth Hokage

Five years after the earlier conflicts, Tsunade and Feng are travelling together when news arrives that Hiruzen has been killed and Konoha is under attack. 56 57

Jiraiya urges Tsunade to accept the Hokage position. After a rock-paper-scissors decision, she returns to Konoha as the Fifth Hokage and appoints Feng as her assistant over the advisors’ objections. 58

Eight-Tails Crisis

When Killer B transforms into the Eight-Tails in Konoha, Tsunade responds as Hokage by summoning Katsuyu and ordering it to heal and protect the civilian population. 74

She later intercepts the Eight-Tails’ strongest attack and subdues the beast with a single overwhelming punch, establishing herself as Konoha’s frontline defender. 77

Akatsuki Assault on Konoha

Tsunade leads Konoha’s response when Akatsuki attacks the village for the Nine-Tails. 110

Using a bracelet fueled by senjutsu chakra, she enters Sage Mode and battles Rinnegan-wielding Uzumaki Feng at extreme speed. 112 With Feng’s Susanoo Armor augmenting her Sage Mode, she reaches the peak of the Super Kage level and helps protect Konoha from catastrophic destruction. 114 115

The battle solidifies Tsunade’s prestige among Konoha’s citizens, while she and Feng direct the village’s reconstruction afterward. 115

Family and the Senju-Uchiha Legacy

Tsunade becomes pregnant with Feng’s child, and the couple chooses the surname Qianyu to represent the union of the Senju and Uchiha clans. 149

Feng revives Nawaki and later resurrects the previous four Hokage so Tsunade can rest during her pregnancy. 147 158 Their daughter Qianyu Xi is born with a Three-Tomoe Sharingan and becomes the focus of Tsunade’s protective instincts. 178 190

Ōtsutsuki and Federation Era

Tsunade continues to defend Konoha against the Ōtsutsuki Clan, entering Sage Mode to repel an advance force alongside Feng. 246

Feng later gives her a Power Fruit, greatly enhancing her strength and granting her aerial mobility and mountain-destroying chakra output. 265 She subsequently joins Feng and Itachi in confronting Ōtsutsuki Shinya on his warship after the enemy places Konoha into an unnatural sleep. 271 272

Parallel-World Reunion

A parallel-world version of Tsunade encounters Qianyu Xi, who arrives in the Shinobi World and identifies herself as Tsunade’s daughter. 320 321

The original Tsunade later accompanies Feng through a spatial-temporal rift to reunite with their daughter and meet their counterparts from the parallel Shinobi World. 328

Notable Quotes

“If it concerns Konoha, don’t come bother me.” 18

“Enough. I’m the doctor, so you have to listen to me.” 37

“Since you already agreed to my request, you’re already mine!” 42

“I’m the Hokage! The responsibility of protecting the village rests on my shoulders!” 77