Vol. 5The Medicine War

Bai Yu defeated Kaido, Nusjuro, and Blackbeard while gathering powerful allies and uncovering the Five Elders’ Devil’s Medicine plot. As Whitebeard’s war against Big Mom unfolded, Bai Yu arrived at Totto Land to save Katakuri, just as Shanks, Mihawk, and Asura Gaban appeared.

  • Kaido revealed the Five Elders’ mission, and Bai Yu’s allies split the enemy forces while Fujitora held off several Elders.
  • Bai Yu killed Kaido and Nusjuro, the remaining Elders fled, and Imu ordered the Five Elders to accelerate their plans.
  • Bai Yu defeated Ryokugyu and accepted World and his crew as allies.
  • Bai Yu defeated Redfield, healed him with a Senzu Bean, and proposed testing how strong he could become with the Bat-Bat Fruit.
  • Bai Yu entered a hell-level dungeon and defeated Madara Uchiha before returning to the world.
  • At Punk Hazard, Blackbeard revealed the Five Elders’ plot and his transformed allies attacked Bai Yu as a familiar voice interrupted them.
  • Bai Yu killed Blackbeard and his allies, then accepted Aokiji into his crew.
  • Whitebeard attacked Totto Land, and Bai Yu saved Katakuri as King charged at him and Shanks arrived with Mihawk and Asura Gaban.
Chapters 401–500 Read from Ch. 401

Arc 17The Battle for Wano

Bai Yu and his allies fought Kaido and the Five Elders in Wano, where Bai Yu killed Kaido and Nusjuro despite their transformations and tricks. Imu ordered the Five Elders to accelerate their plans as news of Bai Yu’s victory reshaped the balance of power.

  • Kaido revealed that four of the Five Elders had come to kill Bai Yu, and Daps said Imu wanted Bai Yu brought back alive or dead.
  • Bai Yu’s allies split the enemy forces as Fujitora’s meteor strikes and Law’s spatial powers delayed the Elders and separated Kaido from Nusjuro.
  • Fujitora used Bai Yu’s Senzu Beans to recover from a fatal wound and held off Daps, Sals, and Killer while Bai Yu fought Kaido.
  • Bai Yu overwhelmed Kaido with his sword techniques and Eight Gates, but Kaido took a crimson pill, regenerated as a devil, and continued fighting.
  • Nusjuro revealed his hidden power and trapped Bai Yu among stone spears, but Bai Yu broke free, cut down Kaido, and marked Nusjuro with a fatal wound.
  • Nusjuro stole Fujitora’s pouch and ate its Senzu Beans, but they did not heal him, and he died as Bai Yu challenged the remaining Elders.
  • The Five Elders fled, and Bai Yu revealed that his fight had left him badly drained as the system advanced his template and granted him White’s Arrancar form.
  • Orochi learned that Kaido and Nusjuro were dead, and Bai Yu mocked the Elders over Den Den Mushi before Killer killed Orochi.
  • Imu ordered the Five Elders to begin their plans early, while news of Bai Yu’s victory spread and Charlotte Linlin worried over Kaido’s death.
Chapters 401–42525 summaries Read

Arc 18Old Monsters and New Allies

Bai Yu gathered World and his crew after defeating Ryokugyu, then tracked down Redfield at Sabaody and beat him in a devastating clash. He healed Redfield with a Senzu Bean and proposed seeing how strong he could become with the Bat-Bat Fruit.

  • King revealed that the Five Elders had given him Devil’s Medicine and promised Charlotte Linlin he could exploit Bai Yu’s attachment to old ties to defeat him.
  • Bai Yu’s group stopped at an island, where he went to a bathhouse alone before meeting the masked Bandy World, who challenged the strength of the new era.
  • World took Bai Yu aboard the Groceade and set sail to attack the Celestial Dragons at Sabaody, where Smoker, Tashigi, Rob Lucci, and Ryokugyu awaited them.
  • World’s enlarged cannon attacks battered the Marine forces, but Ryokugyu stopped the blasts with a Wood Dragon before World collapsed from exhaustion and reunited with his crew.
  • Sanji and Zoro came to Bai Yu’s aid, Fujitora joined his side, and Bai Yu defeated Ryokugyu so quickly that Ryokugyu conceded and withdrew.
  • Bai Yu defeated World in a brief fight, accepted him and his old companions as allies, then warned Ryokugyu that the Five Elders might use Marine Headquarters as pawns.
  • Bai Yu found Redfield at Shakky’s Rip-off Bar, where Redfield attacked Shakky while searching for the Bat-Bat Fruit and Bai Yu challenged him.
  • Bai Yu and Redfield’s clash devastated Island Thirteen, and Bai Yu’s immense black slash left Redfield buried in the ruins.
  • Bai Yu stopped Rayleigh from killing the defeated Redfield and healed him with a Senzu Bean, then offered him liquor and joked about beating him again.
Chapters 426–45025 summaries Read

Arc 19The Devil’s Medicine Plot

Bai Yu cleared a hell-level dungeon by killing Madara Uchiha, then returned to the world and headed to Punk Hazard to intervene in the Admiral duel. There, Blackbeard revealed the Five Elders’ plot and used Devil’s Medicine to transform his prisoners, while a familiar voice interrupted their attack on Bai Yu.

  • Bai Yu defeated Redfield and secured enough System Points to unlock a Dungeon Gate, which dropped onto No. 12 inlet and opened a hell-level dungeon.
  • Bai Yu entered the Naruto world with Rayleigh, Redfield, and Shakky, then followed the system’s mission to defeat Madara Uchiha at the Valley of the End.
  • After Hashirama Senju vanished, Field fought Madara but was overwhelmed, and Bai Yu stepped in to battle Madara’s Perfect Susanoo and Nine-Tails.
  • Bai Yu opened the Eighth Gate and destroyed Madara and the armored Nine-Tails, completing the mission before returning to Island No. 13 with his companions.
  • Garp and Sengoku welcomed Bai Yu back, and Bai Yu explained that the Five Elders had used Devil’s Medicine without informing Marine Headquarters.
  • Bai Yu reached Punk Hazard with his crew, teleported himself and Fujitora to the Aokiji and Akainu duel, and found Blackbeard’s group hiding nearby.
  • Blackbeard revealed that the Five Elders had arranged for him to kill both Admirals, but Aokiji survived and rescued Akainu before Blackbeard’s group attacked Bai Yu.
  • Blackbeard and his allies swallowed Devil’s Medicine and transformed, while Akainu realized the Five Elders had withheld it from the Marines and Shiryu attacked Bai Yu as a familiar voice called the attackers buffoons.
Chapters 451–47525 summaries Read

Arc 20The War for Totto Land

Bai Yu defeated Blackbeard and brought Aokiji into his crew, then urged Whitebeard to abandon his attack on the Big Mom Pirates. Whitebeard went to war anyway, and as Bai Yu arrived to save Katakuri, Shanks appeared with Mihawk and Gaban.

  • Bai Yu killed Shiryu, Burgess, Catarina Devon, and Blackbeard, then refused Akainu’s request to die and accepted Aokiji as a crew member.
  • Jinbe delivered Bai Yu’s warning to Whitebeard, but Whitebeard chose to attack Big Mom, and Bai Yu presented Blackbeard’s head as proof of his defeat.
  • Sengoku learned from Akainu that the Five Elders had conspired with Blackbeard, then named Akainu Fleet Admiral as Marine forces prepared to defend Headquarters.
  • Shanks told Mihawk that he had taken two Devil Fruits from CP0, then recruited Mihawk to join him as he sought greater strength.
  • Big Mom gathered allies and offered Devil’s Medicine, while Zero tried to recruit Red Count Field to help stop Bai Yu and defeat Whitebeard.
  • Whitebeard launched a surprise attack on Totto Land, and his forces battled Big Mom’s army as their clash split Whole Cake Island.
  • Big Mom’s fighters took Devil’s Medicine and transformed, but Bai Yu arrived, saved Katakuri, and faced King as King charged at him.
  • Shanks arrived at Totto Land with Mihawk and Asura Gaban, prompting Whitebeard and Marco to wonder whether he had come to seek peace and a favor.
Chapters 476–50025 summaries Read
Volume 5 of 8
Volume 5 of 8