Arc 21The Aging Potion Trials

Shinji tested successive Aging Potions on demons while training Shion and pursuing a stronger formula. After the Type Three Potion proved less effective than hoped against Kokushibo, Shinji turned to a Type Four Potion and took Neji to the moon, where Toneri confronted him.

  • Kokushibo overwhelmed Sasuke until Haku injected him with the Type Two Aging Potion, and Shinji later sent Haku and Sasuke to test it on Upper Moon Two.
  • Upper Moon Two defeated Sasuke, who survived by using Izanagi at the cost of temporarily losing his right eye, while Shinji resolved to improve the potion.
  • Tsunade’s squad captured Upper Moon Five, but the Type Two Potion strengthened him during a trial, so Shinji used Izanagi to devise a stronger Type Three formula.
  • The Type Three Potion weakened Upper Moon Five in a live trial, and Shinji took Shion to test it on Kokushibo after she demonstrated her sealing technique.
  • Shinji injected Kokushibo with the Type Three Potion, but Kokushibo quickly metabolized it and resurrected from hidden flesh, prompting Shinji and Shion to withdraw.
  • Shinji began planning a Type Four Potion and arranged another lunar trip so Neji could absorb Chakra from the Giant Tenseigan.
  • Shinji and Neji reached the Giant Tenseigan, but Neji’s exoskeleton began absorbing its Chakra, forcing Shinji to seal it as puppets surrounded them.
  • Shinji fought off the Tenseigan puppets while Neji escaped, and Otsutsuki Toneri appeared before him.
Chapters 512–537 Vol. 6 Read

Ch. 512Injecting the Potion

Sasuke fought Kokushibo, but the demon regenerated and nearly shattered Sasuke’s Susanoo before Sasuke trapped him. Haku injected Kokushibo with the Type Two Aging Potion and stopped Sasuke from using his ocular technique so they could see how the potion worked.

  • Kokushibo pulled Sasuke’s arrow from his chest, healed his wound, and restored his broken sword.
  • Kokushibo struck Sasuke’s Susanoo with a powerful Battle Qi blade, carving through its armor.
  • Sasuke’s eyes suddenly hurt, weakening his Susanoo, and Kokushibo battered it until Sasuke fell.
  • Sasuke’s skeletal Susanoo seized Kokushibo as he tried to finish the fight.
  • Haku injected Kokushibo with the Type Two Aging Potion, then stopped Sasuke from using his ocular technique so they could observe its effects.

Ch. 513Grinding

Shinji watched Haku and Sasuke test the Type Two Aging Potion on Upper Moon Two while Sasuke fought recklessly with his Mangekyō Sharingan. After Upper Moon Two survived Amaterasu and cut Sasuke in half, Sasuke's voice unexpectedly rang out behind the demon.

  • Shinji sent Haku and Sasuke to fight Upper Moon Two, hoping to test the Aging Potion and temper Sasuke.
  • Haku injected the Type Two Aging Potion into Upper Moon Two, whose body began rapidly swelling and regenerating.
  • Sasuke used Amaterasu to burn Upper Moon Two, then released his Susanoo as the strain left him exhausted.
  • Upper Moon Two rose from the flames and sliced Sasuke in half at the waist before turning to face Haku.
  • Sasuke's voice suddenly rang out from behind Upper Moon Two, declaring that the demon had angered him.

Ch. 514A Strike!

Sasuke fought Upper Moon Two, survived being cut in half, and crushed the demon with Susanoo, but Upper Moon Two regenerated and escaped after wounding him. Shinji stopped Sasuke from pursuing and concluded that a much stronger Aging Agent was needed to threaten powerful demons.

  • Kokushibo was shocked when Sasuke reappeared unharmed after being cut in half, while Haku stepped aside as Sasuke demanded to fight alone.
  • Sasuke pinned Upper Moon Two with Susanoo, crushed him, and watched Amaterasu burn the scattered flesh to ash.
  • Upper Moon Two burst from beneath the ground, wounded Sasuke with a slash, and tried to attack again before Shinji blocked him with Susanoo.
  • Shinji prevented Sasuke from chasing Upper Moon Two and told him he was no match for the demon.
  • Haku returned the empty Type Two Aging Potion vial, and Shinji decided to develop an Aging Agent at least ten times stronger.

Ch. 515Not the Same!

After Sasuke survived Upper Moon Two by using Izanagi, his right eye lost its Dojutsu and he learned that twisting fate carried a heavy cost. Shinji warned him to use his Mangekyō carefully and left him frustrated by saying their Sharingan were different.

  • Sasuke collapsed in pain, and Shinji found that his right eye had reverted to an ordinary eye after using Izanagi.
  • Shinji ordered Haku to drive off the approaching Kumogakure shinobi, who retreated when they saw Akatsuki guarding the battlefield.
  • Shinji examined Sasuke and explained that his right eye had temporarily lost its Dojutsu.
  • Sasuke asked when his eye would recover, and Shinji said it could take weeks, months, or years.
  • Shinji warned Sasuke to treat his Mangekyō Dojutsu cautiously, then said his Sharingan differed from Shinji's and 'B's.

Ch. 516Capture Operation

After his encounter with Upper Moon Two, Shinji planned to improve the Type Two Aging Potion, but the pharmaceutical team dismissed the need for further work. Meanwhile, Tsunade secured Konoha's approval to capture a stronger Upper Rank, and Danzo raised suspicions about Sasuke's purple Susanoo; Shinji came up with a plan after hearing the news.

  • Shinji reviewed his notes on Upper Moon Two and decided to strengthen the Aging Agent with toxins that could counter demons' bioelectricity and suppress their bodies.
  • Shinji proposed further research to the pharmaceutical team, but its members argued that no living creature could withstand the Type Two Aging Potion and refused to commit resources.
  • At a leadership meeting, Tsunade asked Konoha to capture a stronger Upper Rank for drug trials, and the Third approved her request.
  • Danzo suggested Sasuke might have fought Upper Moon Two using a Shadow Clone, but the Third ended the discussion by saying he would investigate.
  • Tsunade announced the approved capture mission to the research group, and Shinji came up with a plan.

Ch. 517Unbalanced!

Kakashi verified that the Sasuke in Konoha was genuine and had not fought Upper Moon Two. The next day, Tsunade summoned Yakumo and Shinji for an emergency mission, leaving Sasuke resentful that he was not chosen.

  • The Third ordered Kakashi to confirm Sasuke’s identity and explain the purple Susanoo to the Elder Council.
  • Kakashi sparred with Sasuke and concluded that he was the real Sasuke and had not been at the distant battle with Upper Moon Two.
  • Tsunade arrived at the Ninja Academy and gave Yakumo thirty minutes to prepare for an emergency mission.
  • Shion envied Yakumo’s record, while Neji reflected on the mission he still had to complete.
  • Tsunade recruited Shinji for the mission, and Sasuke grew angry that he had not been chosen.

Ch. 518The Upper Rank's Trail

Tsunade led a squad including Shinji to investigate a demon hiding in a Land of Fire village, hoping to capture it alive and learn about the Upper Ranks. Meanwhile, Haku and Karin intercepted the surviving Upper Rank Five nearby.

  • Naruto questioned why Tsunade had recruited Shinji instead of Sasuke, and Sakura chased him after he upset Sasuke.
  • Shinji met Shibi Aburame at the village gates and joined Tsunade, Shizune, Might Guy, and Yakumo for the mission.
  • Tsunade's squad reached the village, and Shibi used blood-sensitive Kikaichū to locate the suspected demon.
  • After nightfall, Shibi pinpointed the target, and Tsunade led the squad into the village with orders to capture it alive.
  • Haku and Karin blocked the Giant Demon, Upper Rank Five, who had survived the battle in Grass Country.

Ch. 519Unexpected Spoils

Tsunade’s squad sealed a weak demon, then encountered a battered demon bearing the Upper Moon Five mark and tried to restrain it. The Upper Moon Five broke free and threatened the squad, leaving the fight unresolved.

  • Tsunade’s squad restrained a demon with chains and Kikaichū while Shizune sealed it in a scroll.
  • Tsunade explained that the mission was A-rank because the demon was weak, and Yakumo accepted the rank.
  • Shibi Aburame’s Kikaichū detected another target, so Tsunade led the squad toward the forest.
  • Tsunade’s squad encountered a battered demon marked Upper Moon Five and attacked it, while Shibi sent Kikaichū to scout the forest.
  • Upper Moon Five broke the adamantine chains and threatened to kill the squad.

Ch. 520One More Free Ride

Tsunade’s squad captured the Upper Moon Five after Yakumo restrained him with Wood Release and Shizune sealed him in a scroll, earning the team credit for an S-rank mission. The news reached the Ninja Academy, where Sasuke brooded over his own failed hunt for the Upper Moon Two.

  • Yakumo trapped the Upper Moon Five in Wood Release while Tsunade’s squad stood guard and waited for him to weaken.
  • Shizune sealed the exhausted Upper Moon Five in a scroll, and Tsunade ordered the squad to return to the village.
  • Tsunade confirmed that capturing the Upper Moon Five counted as an S-rank mission for every squad member, much to Yakumo’s delight and Shinji’s surprise.
  • News of the capture spread through the Ninja Academy the next day, and Sasuke grew vexed by Yakumo and Shinji’s success after his own failed pursuit of the Upper Moon Two.

Ch. 521The Payoff Was Worth It!

Shinji and Yakumo celebrated their successful S-rank mission capturing Upper Moon Five with their classmates over barbecue. After dinner, Shion asked Shinji to talk, leaving him wondering what was troubling her.

  • Yakumo and Shinji told their classmates about capturing Upper Moon Five, while Haku and Karin kept quiet because they had helped lead the demon to Tsunade's squad.
  • Naruto told Sasuke and Sakura that Yakumo was treating everyone to barbecue, but Sasuke refused and vowed to defeat Upper Moon Two.
  • Yakumo and Shinji hosted their classmates at a barbecue restaurant, where the hungry students ate through plate after plate of meat.
  • Shinji ordered more food for the group and reasoned that the expense would support Karin, Kimimaro, and Neji's training projects.
  • After the gathering ended, Shion called Shinji over and asked him to talk; Shinji agreed and asked what was troubling her.

Ch. 522Come and help me save this world!

Shion confronted Shinji about feeling like an outsider and questioned whether he was being honest with her. When her broken bell charm caused her sealed memories to return, she remembered Shinji’s hidden identity and asked to join his organization; Shinji invited her to help save the world.

  • Shion told Shinji she wanted to belong, go on missions, and fight alongside him, and she challenged him about hiding his true self.
  • Shinji noticed that Shion’s bell charm had cracked after she sparred with Yakumo.
  • When Shinji took the charm, Shion remembered that he was Akatsuki Organization’s “A” and asked him not to seal her memories again.
  • Shinji realized Shion’s growing Miko power was harder to suppress and considered how useful it could be against the mysterious man.
  • Shion agreed to learn who Shinji really was, and he invited her to join his organization and help save the world.

Ch. 523Training

Shinji told Shion about the Upper Ranks’ invasion and his plan to counter-invade the Demon Slayer World, and Shion agreed to join him. He began training her in Taijutsu and judged her ready to learn the Breathing Technique.

  • Shinji warned Shion to keep his secret identity hidden, then explained that the Upper Ranks were demons from another world and that he planned to counter-invade their territory.
  • Shion agreed to accompany Shinji and help save the Shinobi World, and he promised to train her intensively.
  • Shinji led Shion to a secluded training ground and explained that Taijutsu would improve her composure and adaptability in battle.
  • Shinji sparred with Shion, gradually increasing the pressure until he kicked her to the ground.
  • Shinji praised Shion’s foundation and said he could begin teaching her the Breathing Technique.

Ch. 524What's My Codename?

Shinji taught Shion Water Breathing and assigned her intensive training in both the technique and the Land of Demons Miko's Sealing Technique. Shion accepted her role in the Akatsuki Organization and asked Shinji for her codename.

  • Shinji explained Water Breathing to Shion and guided her as she quickly learned the basics.
  • Shion felt stronger and lighter, then sparred with Shinji again but lost while distracted by maintaining the technique.
  • Shinji ordered Shion to practice Total Concentration, Constant at all times and train in the Miko's Sealing Technique.
  • Shion asked for her Akatsuki Organization outfit and then asked Shinji what her codename was.

Ch. 525Code Name 'X'

Shinji gave Shion the code name 'X' and explained how his Akatsuki Organization differed from the one Itachi had joined. Shion began training hard with the Breathing Technique, while Sasuke remained resentful toward Shinji and vowed to surpass him and Yakumo.

  • Shinji decided the organization's members would use the village's alphabetical code names, with Shion choosing 'X' for herself.
  • Shinji explained the differences between his Akatsuki Organization and the one Itachi Uchiha and Moryo had joined, and warned Shion to be careful around Dark Dawn.
  • Shion trained with the Breathing Technique at the Ninja Academy and told Shinji she could now use it continuously.
  • Naruto told Sasuke he had missed the barbecue, but Sasuke dismissed it and secretly thought about his unresolved guilt toward Shinji.
  • Sasuke resolved to surpass Shinji and Yakumo in S-rank missions and defeat Upper Moon Two after learning of their recent achievements.

Ch. 526Live Experiment

Shinji and the research team tested the Type Two Aging Potion on a captured demon, which burst apart and turned to ash. The team then prepared to test the potion on Upper Moon Five, while Shinji privately hoped the experiment would reveal its limits and keep the research moving.

  • Tsunade ordered the research team to inject the Type Two Aging Potion into Monster, whose cell division and strength surged before it exploded and vanished into ash.
  • The research team celebrated the apparent success, while Shinji knew the potion would not work on Upper Moon Two and hoped testing it on Upper Moon Five would expose its limits.
  • Shinji told Utatane Koharu that the potion's effectiveness against an Upper Rank remained uncertain, prompting her to consider the issue.
  • Shinji left Koharu's office satisfied that the Advisor Elder Council's pressure would make Tsunade test the potion on Upper Moon Five quickly.
  • The next day, Tsunade announced the Upper Moon Five experiment, and the potion division's ninjas grumbled that the Council had no faith in their work.

Ch. 527The Interrogation and the Unexpected

Tsunade’s team began testing the Type Two Aging Potion on Upper Moon Five, while Konoha’s leaders watched from a temporary stand. The demon’s violent reaction shattered the restraints, leaving the experiment’s safety in question.

  • Tsunade’s team prepared a reinforced cave prison, and Konoha’s leaders and security squads gathered to observe the experiment.
  • The Third told Utatane Koharu that earlier physical and genjutsu interrogations had failed to extract useful information from Upper Moon Five.
  • Tsunade ordered the experiment to begin, and Shizune injected Upper Moon Five with the Type Two Aging Potion.
  • Upper Moon Five roared and strained against his chains as the potion took effect.
  • The chains broke with a thunderous crash, and the Potion Squad ninja stared in disbelief.

Ch. 528Taking a Shortcut

Upper Moon Five broke free during the experiment and was subdued again after Shinji, Yakumo, and the assembled teams intervened. The failed test prompted the research team to revise the Aging Agent, while Shinji planned to use his dojutsu to find the right formula quickly.

  • Upper Moon Five broke its remaining chains and attacked Shizune, but Shinji struck it with Fire Release: Great Fire Annihilation.
  • Yakumo, the Sealing Team, and the Barrier Squad helped restrain and reseal Upper Moon Five as the ANBU evacuated the researchers.
  • Danzo questioned the Potion Team after the Type Two Aging Potion appeared to strengthen Upper Moon Five, and the Third inspected the wreckage before demanding a report.
  • Tsunade accepted responsibility for the failed experiment and rallied the team to improve the Aging Agent.
  • Shinji suggested adding toxins, recorded the team's ideas, and planned to use his dojutsu to identify the right proportions.

Ch. 529Finding Answers in the "Future"

Shinji used Izanagi to search thousands of possible potion formulations and narrow them down to six promising plans. After reproducing and testing them, he selected the potion made using plan 1390 for further consideration.

  • Shinji reviewed the research group's Neurotoxin Hybrid plan and prepared to help optimize the potion formulation.
  • Shinji activated Izanagi and searched nearly two thousand possible formulation attempts, identifying six plans with a reasonable chance of success.
  • Shinji wrote down plans 41, 179, 622, 1231, 1390, and 1683 before the strain on his Sharingan forced him to stop.
  • Shinji reproduced all six formulations and found that plan 622's potion did not become active again.
  • Shinji tested the six potions with instruments, discarded five, and focused on the potion made using plan 1390.

Ch. 530The Commotion and First Credit

Shinji presented a potion he had prepared himself, and testing showed it was a highly potent success that Tsunade named the Type Three Aging Potion. Elsewhere, Shion mastered Water Breathing’s Total Concentration, Constant form as her Miko power began awakening.

  • Tsunade signed the potion team’s supply requests as Shizune reported that more than four hundred experiments had failed to produce a viable potion.
  • Shinji arrived with his own potion, prompting Yakumo and the Medical Team ninja to gather around as he tested it.
  • The equipment showed that Shinji’s potion preserved its potency far better than the Type Two Aging Potion, and Tsunade promised him first credit if live-subject experiments succeeded.
  • Tsunade confirmed the potion was seven to ten times as potent as the Type Two Aging Potion, named it the Type Three Aging Potion, and replanned the live-subject experiments.
  • Shion mastered Water Breathing’s Total Concentration, Constant form, while her weakening bell artifact allowed her Miko power and Sealing Technique abilities to awaken.

Ch. 531The Experiment Succeeded!

Tsunade oversaw a secret live-subject trial of Shinji Uchiha’s Type Three Aging Potion on Upper Moon Five. The potion weakened the demon and suppressed his condition, and Tsunade declared the trial a success.

  • Tsunade reported Shinji Uchiha’s contribution to the Third, who approved a secret live-subject trial of the potion.
  • Tsunade’s team reinforced Upper Moon Five’s cell and had Shizune inject him with the Type Three Aging Potion.
  • The potion caused Upper Moon Five’s body to convulse and rot, while the monitoring instruments failed and the team switched to visual observation.
  • Shinji used his Sharingan and the Byakugan controlled by the Susanoo Lamp to confirm that the potion was devastating Upper Moon Five internally.
  • After about thirty minutes, Upper Moon Five had shrunk, weakened, and lost much of his former strength, though he remained alive.
  • Tsunade confirmed that Upper Moon Five could no longer damage the reinforced cell and declared the live-subject trial a success.

Ch. 532The Shrine Maiden Strikes!

Shinji took Shion to the Land of Iron to test the Type Three Aging Potion and her sealing technique on Upper Moon Two. Shion sealed Kokushibo in a box as soon as they confronted him.

  • After reporting the successful live-subject experiment, Tsunade went to the Hokage Building while Shinji left to meet Shion.
  • Shinji told Shion they would test the potion and her sealing technique on a powerful demon, then used the Lamp to take her to the Land of Iron.
  • Shinji and Shion donned Akatsuki outfits and masks and headed through the snow toward Upper Moon Two.
  • Shinji explained that he chose Upper Moon Two because Upper Moon One was accompanied by Narume and Muku, making him a more difficult target.
  • Shinji and Shion found Kokushibo, and Shion used her Sealing Coffin technique to trap him in a small box.

Ch. 533First Contact and Fierce Battle

Shinji tested Shion’s sealing technique on Upper Moon Two, then had her release him so he could try the Type Three Aging Potion. Upper Moon Two attacked at once, and Shinji protected Shion with Susanoo while secretly weakening its armor to bait his opponent into exposing an opening.

  • Shion sealed Upper Moon Two inside a small box with the Land of Demons Miko’s Sealing Coffin, confirming that her technique worked on demons.
  • Shinji had Shion release Upper Moon Two after moving them farther away, intending to test the Type Three Aging Potion.
  • Upper Moon Two immediately lunged at Shinji and Shion, but Shinji held Shion back and activated Susanoo to block his strike.
  • Upper Moon Two circled Susanoo and repeatedly attacked while Shion grew anxious and Shinji waited for a chance to counter.
  • Shinji secretly weakened Susanoo’s armor to make Upper Moon Two believe his slashes could break through.

Ch. 535Another Trial of the Potion!

Shinji caught Kokushibo in his Susanoo and injected him with a Type Three Aging Potion, but Kokushibo escaped by resurrecting himself from hidden flesh. Shinji returned to Konoha with Shion, planning to find a more effective way to defeat him.

  • Kokushibo built up his strength and attacked a fissure in Shinji's Susanoo, but Shinji anticipated his move and seized him.
  • Shinji injected Kokushibo with a Type Three Aging Potion while Shion watched.
  • The potion rapidly decayed Kokushibo's skin, but Shinji noticed that his internal tissues remained intact and the toxin was being metabolized quickly.
  • Shinji crushed Kokushibo's body, then realized Kokushibo had used a secret technique to resurrect himself from flesh hidden elsewhere.
  • Shinji told Shion the potion had been less effective than expected, and they returned to Konoha without pursuing Kokushibo.

Ch. 536526: Keep Moving Forward!

After returning to Konoha, Shinji planned how to capture the mysterious man and protect the Shinobi World, concluding that he needed to advance his Rinnegan or Tenseigan plans before invading the Demon Slayer World. He prepared to improve the Aging Agent and arranged another trip to the moon to help Neji store Chakra.

  • Shinji and Shion returned to Konoha, and he told her to reflect on the battle and keep it secret.
  • Shinji decided the Type Three Aging Potion might not weaken the mysterious man enough, but resolved to refine it and rely on his own strength.
  • Shinji reviewed his Rinnegan and Tenseigan plans, noting Karin's limited remaining role and Sasuke's slow path toward awakening the Rinnegan.
  • Shinji determined that Neji needed Chakra from the Giant Tenseigan on the moon to keep pace with Kimimaro's Chakra accumulation.
  • Shinji consulted the pharmacists, arranged for Kusagakure to gather rare toxins, and began preparing to make a Type Four Aging Potion.
  • Shinji used Naobi to tell Neji to prepare for another trip to the moon, and Neji felt both apprehension and anticipation.

Ch. 537An Accident on the Moon

Shinji and Neji infiltrated the Otsutsuki Branch Family’s castle on the moon so Neji could absorb Chakra from the Giant Tenseigan, but Neji’s biological exoskeleton absorbed Chakra uncontrollably and alerted the clan. Shinji fought through the Tenseigan puppets to help Neji escape, then encountered Otsutsuki Toneri.

  • Shinji and Neji traveled to the moon, met Karin, and secretly crossed the barrier to reach the Otsutsuki Branch Family’s castle.
  • They found the castle’s defenses strengthened but made their way to the temple housing the Giant Tenseigan.
  • Neji absorbed Tenseigan Chakra, but his biological exoskeleton activated and began absorbing Chakra on its own.
  • Shinji sealed the exoskeleton, and he and Neji fled as the Giant Tenseigan reacted and Tenseigan puppets surrounded them.
  • Shinji fought through the puppets while Neji escaped, then Otsutsuki Toneri appeared before Shinji.
Arc 21 of 62